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MGMT O-6-methylguanine-DNA methyltransferase [ Panthera tigris (tiger) ]

Gene ID: 102964226, updated on 10-Mar-2024

Summary

Gene symbol
MGMT
Gene description
O-6-methylguanine-DNA methyltransferase
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
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Genomic context

Location:
chromosome: D2
Exon count:
10
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) D2 NC_056670.1 (83567107..83865649)

Chromosome D2 - NC_056670.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122232032 Neighboring gene uncharacterized LOC122232029 Neighboring gene uncharacterized LOC122231720 Neighboring gene uncharacterized LOC122231866 Neighboring gene uncharacterized LOC122231867 Neighboring gene EBF transcription factor 3

Genomic regions, transcripts, and products

Genomic Sequence:
NC_056670.1 Chromosome D2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methylated-DNA-[protein]-cysteine S-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
methylated-DNA--protein-cysteine methyltransferase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056670.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    83567107..83865649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042959907.1XP_042815841.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

    Conserved Domains (1) summary
    COG0350
    Location:13178
    AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
  2. XM_042959906.1XP_042815840.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

    Conserved Domains (1) summary
    COG0350
    Location:13178
    AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
  3. XM_042959904.1XP_042815838.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

    Conserved Domains (1) summary
    COG0350
    Location:13178
    AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
  4. XM_042959905.1XP_042815839.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

    Conserved Domains (1) summary
    COG0350
    Location:13178
    AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
  5. XM_042959908.1XP_042815842.1  methylated-DNA--protein-cysteine methyltransferase isoform X1

    Conserved Domains (1) summary
    COG0350
    Location:13178
    AdaB; O6-methylguanine-DNA--protein-cysteine methyltransferase [Replication, recombination and repair]
  6. XM_042959909.1XP_042815843.1  methylated-DNA--protein-cysteine methyltransferase isoform X2

    Conserved Domains (1) summary
    TIGR00589
    Location:97176
    ogt; O-6-methylguanine DNA methyltransferase
  7. XM_042959910.1XP_042815844.1  methylated-DNA--protein-cysteine methyltransferase isoform X3

    Conserved Domains (1) summary
    TIGR00589
    Location:87166
    ogt; O-6-methylguanine DNA methyltransferase