U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MTA1 metastasis associated 1 [ Panthera tigris (tiger) ]

Gene ID: 102961823, updated on 10-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
MTA1
Gene description
metastasis associated 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MTA1 in Genome Data Viewer
Location:
chromosome: B3
Exon count:
22
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) B3 NC_056665.1 (145826188..145861295)

Chromosome B3 - NC_056665.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107180836 Neighboring gene testis expressed 22 Neighboring gene uncharacterized LOC122239730 Neighboring gene cysteine rich protein 2 Neighboring gene cysteine rich protein 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_056665.1 Chromosome B3 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to ionizing radiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
metastasis-associated protein MTA1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056665.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    145826188..145861295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042990749.1 → XP_042846683.1  metastasis-associated protein MTA1 isoform X1

    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  2. XM_042990750.1 → XP_042846684.1  metastasis-associated protein MTA1 isoform X2

    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  3. XM_042990751.1 → XP_042846685.1  metastasis-associated protein MTA1 isoform X3

    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  4. XM_042990752.1 → XP_042846686.1  metastasis-associated protein MTA1 isoform X4

    Conserved Domains (3) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.