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HIF3A hypoxia inducible factor 3 subunit alpha [ Elephantulus edwardii (Cape elephant shrew) ]

Gene ID: 102846475, updated on 10-Mar-2024

Summary

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Gene symbol
HIF3A
Gene description
hypoxia inducible factor 3 subunit alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Elephantulus edwardii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Macroscelidea; Macroscelididae; Elephantulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
100 current EleEdw1.0 (GCF_000299155.1) Unplaced Scaffold NW_006399986.1 (39315..78246)

NW_006399986.1Genomic Context describing neighboring genes Neighboring gene protein slowmo homolog 2-like Neighboring gene protein phosphatase 5 catalytic subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006399986 unplaced scaffold reference EleEdw1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypoxia-inducible factor 3-alpha
Names
hypoxia inducible factor 3 alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Elephantulus edwardii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EleEdw1.0

Genomic

  1. NW_006399986.1 Reference EleEdw1.0

    Range
    39315..78246
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006898689.1 → XP_006898751.1  hypoxia-inducible factor 3-alpha

    Conserved Domains (4) summary
    cd00083
    Location:13 → 68
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:241 → 338
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:251 → 338
    PAS_3; PAS fold
    pfam11413
    Location:480 → 509
    HIF-1; Hypoxia-inducible factor-1
Nucleotide Protein
Heading Accession and Version

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