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masp2 MBL associated serine protease 2 [ Lepisosteus oculatus (spotted gar) ]

Gene ID: 102693055, updated on 10-Mar-2024

Summary

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Gene symbol
masp2
Gene description
MBL associated serine protease 2
See related
Ensembl:ENSLOCG00000006509
Gene type
protein coding
RefSeq status
MODEL
Organism
Lepisosteus oculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG25
Exon count:
11
Annotation release Status Assembly LG Location
101 current LepOcu1 (GCF_000242695.1) LG25 NC_023203.1 (11751046..11763323)

Linkage Group LG25 - NC_023203.1Genomic Context describing neighboring genes Neighboring gene cortistatin Neighboring gene uncharacterized LOC107075516 Neighboring gene DNA fragmentation factor, alpha polypeptide Neighboring gene peroxisomal biogenesis factor 14 Neighboring gene uncharacterized LOC107075539

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_023203.1 Chromosome LG25 Reference LepOcu1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan-binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lepisosteus oculatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepOcu1 Primary Assembly

Genomic

  1. NC_023203.1 Reference LepOcu1 Primary Assembly

    Range
    11751046..11763323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015336880.1 → XP_015192366.1  mannan-binding lectin serine protease 2

    UniProtKB/TrEMBL
    W5MHL3
    Related
    ENSLOCP00000007872.1, ENSLOCT00000007882.1
    Conserved Domains (7) summary
    cd00033
    Location:297 → 358
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00020
    Location:438 → 680
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:25 → 131
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00041
    Location:181 → 292
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:439 → 683
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:363 → 424
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:149 → 177
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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