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kdr kinase insert domain receptor (a type III receptor tyrosine kinase) [ Lepisosteus oculatus (spotted gar) ]

Gene ID: 102682636, updated on 10-Mar-2024

Summary

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Gene symbol
kdr
Gene description
kinase insert domain receptor (a type III receptor tyrosine kinase)
See related
Ensembl:ENSLOCG00000014177
Gene type
protein coding
RefSeq status
MODEL
Organism
Lepisosteus oculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae; Lepisosteus
Orthologs
human zebrafish all
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Genomic context

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See kdr in Genome Data Viewer
Location:
chromosome: LG4
Exon count:
30
Annotation release Status Assembly LG Location
101 current LepOcu1 (GCF_000242695.1) LG4 NC_023182.1 (73170519..73193000, complement)

Linkage Group LG4 - NC_023182.1Genomic Context describing neighboring genes Neighboring gene KIT proto-oncogene, receptor tyrosine kinase a Neighboring gene uncharacterized LOC107077165

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_023182.1 Chromosome LG4 Reference LepOcu1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vascular endothelial growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endothelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vascular endothelial growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vascular endothelial growth factor receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lepisosteus oculatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepOcu1 Primary Assembly

Genomic

  1. NC_023182.1 Reference LepOcu1 Primary Assembly

    Range
    73170519..73193000 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015345978.1 → XP_015201464.1  vascular endothelial growth factor receptor 2 isoform X2

    UniProtKB/TrEMBL
    W5NA14
    Conserved Domains (7) summary
    smart00408
    Location:682 → 744
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:47 → 124
    IG; Immunoglobulin
    smart00410
    Location:241 → 324
    IG_like; Immunoglobulin like
    pfam07679
    Location:667 → 754
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:834 → 1161
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:242 → 328
    Ig; Immunoglobulin domain
    cl21453
    Location:826 → 1168
    PKc_like; Protein Kinases, catalytic domain

  2. XM_015345977.1 → XP_015201463.1  vascular endothelial growth factor receptor 2 isoform X1

    UniProtKB/TrEMBL
    W5NA10, W5NA14
    Related
    ENSLOCP00000017469.1, ENSLOCT00000017500.1
    Conserved Domains (7) summary
    smart00408
    Location:682 → 744
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:47 → 124
    IG; Immunoglobulin
    smart00410
    Location:241 → 324
    IG_like; Immunoglobulin like
    pfam07679
    Location:667 → 754
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:834 → 1161
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:242 → 328
    Ig; Immunoglobulin domain
    cl21453
    Location:826 → 1168
    PKc_like; Protein Kinases, catalytic domain

  3. XM_015345979.1 → XP_015201465.1  vascular endothelial growth factor receptor 2 isoform X3

    UniProtKB/TrEMBL
    W5NA14
    Conserved Domains (7) summary
    smart00408
    Location:682 → 744
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:47 → 124
    IG; Immunoglobulin
    smart00410
    Location:241 → 324
    IG_like; Immunoglobulin like
    pfam07679
    Location:667 → 754
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:834 → 1161
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:242 → 328
    Ig; Immunoglobulin domain
    cl21453
    Location:826 → 1168
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_001478294.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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