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LOC102509559 tyrosine-protein kinase ZAP-70 [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102509559, updated on 11-Apr-2024

Summary

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Gene symbol
LOC102509559
Gene description
tyrosine-protein kinase ZAP-70
Locus tag
CB1_000321012
See related
EnsemblRapid:ENSCFEG00005016187
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Also known as
ZAP70
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 28
Exon count:
15
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 28 NC_045723.1 (2977219..2997517, complement)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006210497.1 (657195..677916, complement)

Chromosome 28 - NC_045723.1Genomic Context describing neighboring genes Neighboring gene UPF0449 protein C19orf25 homolog Neighboring gene transmembrane protein 131 Neighboring gene chromosome 28 C2orf92 homolog Neighboring gene actin related protein 1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ZAP-70
Names
zeta-chain (TCR) associated protein kinase 70kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045723.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    2977219..2997517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032469627.1 → XP_032325518.1  tyrosine-protein kinase ZAP-70 isoform X2

    UniProtKB/TrEMBL
    A0A8B8S5M7
    Related
    ENSCFEP00005026881.1, ENSCFET00005029894.1
    Conserved Domains (3) summary
    cd09938
    Location:8 → 111
    SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
    cd10402
    Location:152 → 256
    SH2_C-SH2_Zap70; C-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70)
    cd05115
    Location:331 → 599
    PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa

  2. XM_032469626.1 → XP_032325517.1  tyrosine-protein kinase ZAP-70 isoform X1

    UniProtKB/TrEMBL
    A0A8B8S7Q0
    Related
    ENSCFEP00005026912.1, ENSCFET00005029928.1
    Conserved Domains (3) summary
    cd09938
    Location:27 → 130
    SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
    cd10402
    Location:171 → 275
    SH2_C-SH2_Zap70; C-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70)
    cd05115
    Location:350 → 618
    PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa

  3. XM_032469628.1 → XP_032325519.1  tyrosine-protein kinase ZAP-70 isoform X3

    UniProtKB/TrEMBL
    A0A8B8S747
    Conserved Domains (2) summary
    cl15255
    Location:1 → 96
    SH2; Src homology 2 (SH2) domain
    cl21453
    Location:171 → 439
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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