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iqgap1 IQ motif containing GTPase activating protein 1 [ Haplochromis burtoni (Burton's mouthbrooder) ]

Gene ID: 102298894, updated on 10-Mar-2024

Summary

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Gene symbol
iqgap1
Gene description
IQ motif containing GTPase activating protein 1
See related
Ensembl:ENSHBUG00000002832
Gene type
protein coding
RefSeq status
MODEL
Organism
Haplochromis burtoni
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Haplochromis
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
37
Annotation release Status Assembly Chr Location
102 current NCSU_Asbu1 (GCF_018398535.1) Unplaced Scaffold NW_024582592.1 (606706..649138)
101 previous assembly AstBur1.0 (GCF_000239415.1) Unplaced Scaffold NW_005179636.1 (359898..402164, complement)

NW_024582592.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene cocaine- and amphetamine-regulated transcript-like Neighboring gene CREB regulated transcription coactivator 3 Neighboring gene ADAMTS like 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating-like protein IQGAP1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haplochromis burtoni Annotation Release 102

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NCSU_Asbu1 Primary Assembly

Genomic

  1. NW_024582592.1 Reference NCSU_Asbu1 Primary Assembly

    Range
    606706..649138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005937933.3 → XP_005937995.1  ras GTPase-activating-like protein IQGAP1

    UniProtKB/TrEMBL
    A0A3Q2W9Y8
    Related
    ENSHBUP00000022513.1
    Conserved Domains (6) summary
    smart00015
    Location:803 → 823
    IQ; Calmodulin-binding motif
    smart00323
    Location:989 → 1340
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:43 → 157
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00201
    Location:680 → 708
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam03836
    Location:1451 → 1576
    RasGAP_C; RasGAP C-terminus
    cl02569
    Location:1000 → 1379
    RasGAP; Ras GTPase Activating Domain
Nucleotide Protein
Heading Accession and Version

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