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dlg3 discs, large homolog 3 (Drosophila) [ Xiphophorus maculatus (southern platyfish) ]

Gene ID: 102229662, updated on 10-Mar-2024

Summary

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Gene symbol
dlg3
Gene description
discs, large homolog 3 (Drosophila)
See related
Ensembl:ENSXMAG00000013224
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus maculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 23
Exon count:
28
Annotation release Status Assembly Chr Location
102 current X_maculatus-5.0-male (GCF_002775205.1) 23 NC_036465.1 (7017393..7136433, complement)
101 previous assembly Xiphophorus_maculatus-4.4.2 (GCF_000241075.1) Unplaced Scaffold NW_005372216.1 (626169..721556, complement)

Chromosome 23 - NC_036465.1Genomic Context describing neighboring genes Neighboring gene kinase insert domain receptor like Neighboring gene testis-expressed protein 11-like Neighboring gene testis expressed 11 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene uncharacterized LOC111606975 Neighboring gene PDZ domain containing 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disks large homolog 3
Names
discs large MAGUK scaffold protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus maculatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference X_maculatus-5.0-male Primary Assembly

Genomic

  1. NC_036465.1 Reference X_maculatus-5.0-male Primary Assembly

    Range
    7017393..7136433 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023328797.1 → XP_023184565.1  disks large homolog 3 isoform X5

    UniProtKB/TrEMBL
    A0A3B5R966
    Related
    ENSXMAP00000039654.1, ENSXMAT00000031497.1
    Conserved Domains (6) summary
    cd12029
    Location:562 → 628
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:444 → 522
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:719 → 897
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:8 → 63
    L27_1
    pfam10600
    Location:328 → 399
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:87 → 147
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  2. XM_023328796.1 → XP_023184564.1  disks large homolog 3 isoform X4

    UniProtKB/TrEMBL
    A0A3B5R966
    Related
    ENSXMAP00000030033.1, ENSXMAT00000041029.1
    Conserved Domains (6) summary
    cd12029
    Location:567 → 633
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:449 → 527
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:724 → 902
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:11 → 68
    L27_1
    pfam10600
    Location:333 → 404
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:92 → 152
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  3. XM_023328795.1 → XP_023184563.1  disks large homolog 3 isoform X3

    UniProtKB/TrEMBL
    M4AFN7
    Conserved Domains (6) summary
    cd12029
    Location:570 → 636
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:452 → 530
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:727 → 905
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 407
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  4. XM_023328798.1 → XP_023184566.1  disks large homolog 3 isoform X6

    UniProtKB/TrEMBL
    M4AFN7
    Conserved Domains (6) summary
    cd12029
    Location:576 → 642
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:458 → 536
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:714 → 892
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 413
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  5. XM_023328794.1 → XP_023184562.1  disks large homolog 3 isoform X2

    UniProtKB/TrEMBL
    M4AFN7
    Conserved Domains (6) summary
    cd12029
    Location:576 → 642
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:458 → 536
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:732 → 910
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 413
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  6. XM_023328793.1 → XP_023184561.1  disks large homolog 3 isoform X1

    UniProtKB/TrEMBL
    M4AFN7
    Conserved Domains (6) summary
    cd12029
    Location:576 → 642
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:458 → 536
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:733 → 911
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 413
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  7. XM_023328799.1 → XP_023184567.1  disks large homolog 3 isoform X7

    UniProtKB/TrEMBL
    M4AFN7
    Conserved Domains (6) summary
    cd12029
    Location:534 → 600
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:416 → 494
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:691 → 869
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 417
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  8. XM_005799493.3 → XP_005799550.2  disks large homolog 3 isoform X9

    UniProtKB/TrEMBL
    M4AFN7
    Conserved Domains (6) summary
    cd12029
    Location:528 → 594
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:410 → 488
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:666 → 844
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 411
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  9. XM_023328800.1 → XP_023184568.1  disks large homolog 3 isoform X8

    UniProtKB/TrEMBL
    M4AFN7
    Related
    ENSXMAP00000013281.2, ENSXMAT00000013297.2
    Conserved Domains (6) summary
    cd12029
    Location:528 → 594
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:255 → 344
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:410 → 488
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:685 → 863
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:342 → 411
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:121 → 161
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
Nucleotide Protein Strain
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