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dlg3 discs, large homolog 3 (Drosophila) [ Danio rerio (zebrafish) ]

Gene ID: 564081, updated on 9-Sep-2018

Summary

Official Symbol
dlg3provided by ZNC
Official Full Name
discs, large homolog 3 (Drosophila)provided by ZNC
Primary source
ZFIN:ZDB-GENE-050208-93
See related
Ensembl:ENSDARG00000076796 Vega:OTTDARG00000042763
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
fa66c08; fa66e02; fd02c12; fu95c12; im:7138640; wu:fa66c08; wu:fa66e02; wu:fd02c12; wu:fu95c12; si:ch211-276g21.1
Orthologs

Genomic context

See dlg3 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
30
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (33070242..33218142, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (32729953..32877822, complement)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene caudal type homeobox 4 Neighboring gene kinase insert domain receptor like Neighboring gene testis expressed 11 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene PDZ domain containing 11

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC162970

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ionotropic glutamate receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment or maintenance of epithelial cell apical/basal polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor clustering IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor localization to synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with ionotropic glutamate receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuromuscular junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic density membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    33070242..33218142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481213.1XP_021336888.1  disks large homolog 3 isoform X18

    Related
    ENSDARP00000069206.4, ENSDART00000074720.7
    Conserved Domains (2) summary
    cd12029
    Location:1985
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
  2. XM_021481197.1XP_021336872.1  disks large homolog 3 isoform X2

    Conserved Domains (6) summary
    cd12029
    Location:570634
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:452530
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:744922
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:360
    L27_1
    pfam10600
    Location:325404
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:84144
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_021481203.1XP_021336878.1  disks large homolog 3 isoform X8

    Conserved Domains (5) summary
    cd12029
    Location:557621
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:438522
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:132216
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:731909
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:312391
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  4. XM_021481208.1XP_021336883.1  disks large homolog 3 isoform X13

    Conserved Domains (5) summary
    cd12029
    Location:520584
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:402480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:694872
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_021481198.1XP_021336873.1  disks large homolog 3 isoform X3

    Conserved Domains (6) summary
    cd12029
    Location:569633
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:450534
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:743921
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  6. XM_021481207.1XP_021336882.1  disks large homolog 3 isoform X12

    Conserved Domains (5) summary
    cd12029
    Location:526590
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:408486
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:700878
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  7. XM_021481206.1XP_021336881.1  disks large homolog 3 isoform X11

    Conserved Domains (6) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:713891
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  8. XM_021481204.1XP_021336879.1  disks large homolog 3 isoform X9

    Conserved Domains (6) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:723901
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  9. XM_021481199.1XP_021336874.1  disks large homolog 3 isoform X4

    Conserved Domains (5) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:457535
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:741919
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  10. XM_021481205.1XP_021336880.1  disks large homolog 3 isoform X10

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:721899
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  11. XM_021481200.1XP_021336875.1  disks large homolog 3 isoform X5

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:739917
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  12. XM_021481202.1XP_021336877.1  disks large homolog 3 isoform X7

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:731909
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  13. XM_021481196.1XP_021336871.1  disks large homolog 3 isoform X1

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:749927
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  14. XM_021481211.1XP_021336886.1  disks large homolog 3 isoform X16

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:383467
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:132216
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:312385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  15. XM_021481210.1XP_021336885.1  disks large homolog 3 isoform X15

    Conserved Domains (5) summary
    cd12029
    Location:520586
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:402480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  16. XM_021481209.1XP_021336884.1  disks large homolog 3 isoform X14

    Related
    ENSDARP00000073316.6, ENSDART00000078856.7
    Conserved Domains (5) summary
    cd12029
    Location:520586
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:402480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:686864
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  17. XM_021481201.1XP_021336876.1  disks large homolog 3 isoform X6

    Related
    ENSDARP00000157371.1, ENSDART00000180583.1
    Conserved Domains (5) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:457535
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:731909
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  18. XM_021481212.1XP_021336887.1  disks large homolog 3 isoform X17

    Conserved Domains (3) summary
    smart00228
    Location:31115
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam00625
    Location:324502
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:150214
    SH3; Src Homology 3 domain superfamily

RNA

  1. XR_002459956.1 RNA Sequence

  2. XR_002459957.1 RNA Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394917.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    43184..190341 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009291194.3XP_009289469.1  disks large homolog 3 isoform X18

    See identical proteins and their annotated locations for XP_009289469.1

    UniProtKB/TrEMBL
    A5PKT0
    Related
    OTTDARP00000049130
    Conserved Domains (2) summary
    cd12029
    Location:1985
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    pfam00625
    Location:175353
    Guanylate_kin; Guanylate kinase
  2. XM_021472841.1XP_021328516.1  disks large homolog 3 isoform X2

    Conserved Domains (6) summary
    cd12029
    Location:570634
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:452530
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:744922
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:360
    L27_1
    pfam10600
    Location:325404
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:84144
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_021472846.1XP_021328521.1  disks large homolog 3 isoform X8

    Conserved Domains (5) summary
    cd12029
    Location:557621
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:438522
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:132216
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:731909
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:312391
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  4. XM_021472842.1XP_021328517.1  disks large homolog 3 isoform X3

    Conserved Domains (6) summary
    cd12029
    Location:569633
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:450534
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:743921
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_021472848.1XP_021328523.1  disks large homolog 3 isoform X10

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:721899
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  6. XM_021472845.1XP_021328520.1  disks large homolog 3 isoform X7

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:731909
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  7. XM_021472840.1XP_021328515.1  disks large homolog 3 isoform X1

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:749927
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  8. XM_021472850.1XP_021328525.1  disks large homolog 3 isoform X13

    Conserved Domains (5) summary
    cd12029
    Location:520584
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:402480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:694872
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  9. XM_021472849.1XP_021328524.1  disks large homolog 3 isoform X12

    Conserved Domains (5) summary
    cd12029
    Location:526590
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:408486
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:700878
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  10. XM_009291187.3XP_009289462.1  disks large homolog 3 isoform X9

    Conserved Domains (6) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:723901
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  11. XM_021472843.1XP_021328518.1  disks large homolog 3 isoform X4

    Conserved Domains (5) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:457535
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:741919
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  12. XM_021472844.1XP_021328519.1  disks large homolog 3 isoform X5

    Conserved Domains (6) summary
    cd12029
    Location:575639
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:739917
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  13. XM_021472851.1XP_021328526.1  disks large homolog 3 isoform X14

    Conserved Domains (5) summary
    cd12029
    Location:520586
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:402480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:686864
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  14. XM_009291189.3XP_009289464.1  disks large homolog 3 isoform X11

    Conserved Domains (6) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:456540
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:150234
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:713891
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  15. XM_009291184.3XP_009289459.1  disks large homolog 3 isoform X6

    Conserved Domains (5) summary
    cd12029
    Location:575641
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:457535
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:731909
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330409
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  16. XM_009291193.3XP_009289468.1  disks large homolog 3 isoform X16

    Conserved Domains (5) summary
    cd12029
    Location:502568
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00228
    Location:383467
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:132216
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:640818
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:312385
    PDZ_assoc; PDZ-associated domain of NMDA receptors
  17. XM_009291192.3XP_009289467.1  disks large homolog 3 isoform X15

    Conserved Domains (5) summary
    cd12029
    Location:520586
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    cd00992
    Location:402480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:658836
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:330403
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:109149
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  18. XM_021472852.1XP_021328527.1  disks large homolog 3 isoform X17

    Conserved Domains (3) summary
    smart00228
    Location:31115
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    pfam00625
    Location:324502
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:150214
    SH3; Src Homology 3 domain superfamily

RNA

  1. XR_002457389.1 RNA Sequence

  2. XR_002457388.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001098742.1: Suppressed sequence

    Description
    NM_001098742.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: DLG3 (GeneID:1741).
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