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Dusp8 dual specificity phosphatase 8 [ Chinchilla lanigera (long-tailed chinchilla) ]

Gene ID: 102029618, updated on 10-Mar-2024

Summary

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Gene symbol
Dusp8
Gene description
dual specificity phosphatase 8
See related
Ensembl:ENSCLAG00000001311
Gene type
protein coding
RefSeq status
MODEL
Organism
Chinchilla lanigera
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Chinchillidae; Chinchilla
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See Dusp8 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
6
Annotation release Status Assembly Chr Location
101 current ChiLan1.0 (GCF_000276665.1) Unplaced Scaffold NW_004955476.1 (10816647..10826787)

NW_004955476.1Genomic Context describing neighboring genes Neighboring gene protein FAM133-like Neighboring gene eukaryotic translation initiation factor 3 subunit M Neighboring gene coiled-coil domain containing 73 Neighboring gene uncharacterized LOC102028530 Neighboring gene MOB kinase activator 2 Neighboring gene BR serine/threonine kinase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004955476.1 Unplaced Scaffold Reference ChiLan1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chinchilla lanigera Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ChiLan1.0 Primary Assembly

Genomic

  1. NW_004955476.1 Reference ChiLan1.0 Primary Assembly

    Range
    10816647..10826787
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013503009.1 → XP_013358463.1  dual specificity protein phosphatase 8

    UniProtKB/TrEMBL
    A0A8C2YIS7
    Related
    ENSCLAP00000001761.1, ENSCLAT00000001804.1
    Conserved Domains (2) summary
    cd00127
    Location:160 → 297
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    cd01446
    Location:10 → 137
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
Nucleotide Protein
Heading Accession and Version

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