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EPO erythropoietin [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101925524, updated on 12-Jun-2024

Summary

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Gene symbol
EPO
Gene description
erythropoietin
See related
Ensembl:ENSMFAG00000044414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See EPO in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 3 NC_088377.1 (49318373..49321643)
102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 3 NC_052257.1 (167191359..167194378)

Chromosome 3 - NC_088377.1Genomic Context describing neighboring genes Neighboring gene GRB10 interacting GYF protein 1 Neighboring gene POP7 homolog, ribonuclease P/MRP subunit Neighboring gene zonadhesin Neighboring gene EPH receptor B4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Monkey erythropoietin gene: cloning, expression and comparison with the human erythropoietin gene. Lin FK, et al. Gene, 1986. PMID 2877922

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables erythropoietin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in erythropoietin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
erythropoietin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284561.1 → NP_001271490.1  erythropoietin precursor

    Status: VALIDATED

    Source sequence(s)
    AQIA01045461
    UniProtKB/Swiss-Prot
    P07865
    Conserved Domains (1) summary
    pfam00758
    Location:31 → 191
    EPO_TPO; Erythropoietin/thrombopoietin

RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.0

Genomic

  1. NC_088377.1 Reference T2T-MFA8v1.0

    Range
    49318373..49321643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045387355.2 → XP_045243290.1  erythropoietin isoform X1

    UniProtKB/TrEMBL
    A0A2K5VM76
    Conserved Domains (1) summary
    pfam00758
    Location:31 → 192
    EPO_TPO; Erythropoietin/thrombopoietin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07865.1 GenPept UniProtKB/Swiss-Prot:P07865

Gene LinkOut

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