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Dab2 DAB adaptor protein 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101725399, updated on 8-Mar-2024

Summary

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Gene symbol
Dab2
Gene description
DAB adaptor protein 2
Locus tag
GW7_20807
See related
Ensembl:ENSHGLG00000003257
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624759.1 (15459436..15520225)

NW_004624759.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S24 pseudogene Neighboring gene uncharacterized LOC110350070 Neighboring gene activator of 90 kDa heat shock protein ATPase homolog 1 pseudogene Neighboring gene complement C9 Neighboring gene oxysterol-binding protein-related protein 9-like Neighboring gene FYN binding protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624759 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disabled homolog 2
Names
DAB2, clathrin adaptor protein
Disabled-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624759.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    15459436..15520225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021261471.1 → XP_021117130.1  disabled homolog 2 isoform X3

    UniProtKB/TrEMBL
    G5AND9
    Conserved Domains (2) summary
    cd01215
    Location:35 → 172
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:394 → 752
    Atrophin-1; Atrophin-1 family

  2. XM_004848584.3 → XP_004848641.1  disabled homolog 2 isoform X3

    See identical proteins and their annotated locations for XP_004848641.1

    UniProtKB/TrEMBL
    G5AND9
    Related
    ENSHGLP00000004456.1, ENSHGLT00000004518.1
    Conserved Domains (2) summary
    cd01215
    Location:35 → 172
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:394 → 752
    Atrophin-1; Atrophin-1 family

  3. XM_021261468.1 → XP_021117127.1  disabled homolog 2 isoform X1

    Conserved Domains (2) summary
    cd01215
    Location:86 → 223
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:445 → 643
    Atrophin-1; Atrophin-1 family

  4. XM_021261469.1 → XP_021117128.1  disabled homolog 2 isoform X1

    Conserved Domains (2) summary
    cd01215
    Location:86 → 223
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:445 → 643
    Atrophin-1; Atrophin-1 family

  5. XM_021261470.1 → XP_021117129.1  disabled homolog 2 isoform X2

    Conserved Domains (2) summary
    cd01215
    Location:86 → 223
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:424 → 622
    Atrophin-1; Atrophin-1 family

  6. XM_021261472.1 → XP_021117131.1  disabled homolog 2 isoform X4

    Related
    ENSHGLP00000004458.1, ENSHGLT00000004520.1
    Conserved Domains (2) summary
    cd01215
    Location:86 → 223
    PTB_Dab; Disabled (Dab) Phosphotyrosine-binding domain
    cl26464
    Location:273 → 425
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
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