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LOC101724157 lanosterol 14-alpha demethylase [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101724157, updated on 8-Mar-2024

Summary

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Gene symbol
LOC101724157
Gene description
lanosterol 14-alpha demethylase
Locus tag
GW7_20514
See related
Ensembl:ENSHGLG00000016647
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See LOC101724157 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624809.1 (1080427..1110802)

NW_004624809.1Genomic Context describing neighboring genes Neighboring gene transcription intermediary factor 1-beta pseudogene Neighboring gene leucine rich repeats and death domain containing 1 Neighboring gene A-kinase anchoring protein 9 Neighboring gene uncharacterized LOC106010860 Neighboring gene heat shock protein HSP 90-beta pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624809 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in sterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lanosterol 14-alpha demethylase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624809.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    1080427..1110802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004862375.3 → XP_004862432.1  lanosterol 14-alpha demethylase isoform X4

    Conserved Domains (1) summary
    cl12078
    Location:1 → 378
    p450; Cytochrome P450

  2. XM_021242589.1 → XP_021098248.1  lanosterol 14-alpha demethylase isoform X2

    Conserved Domains (1) summary
    cl12078
    Location:61 → 444
    p450; Cytochrome P450

  3. XM_013078732.2 → XP_012934186.1  lanosterol 14-alpha demethylase isoform X3

    Conserved Domains (1) summary
    cl12078
    Location:61 → 448
    p450; Cytochrome P450

  4. XM_004862373.3 → XP_004862430.1  lanosterol 14-alpha demethylase isoform X1

    See identical proteins and their annotated locations for XP_004862430.1

    UniProtKB/TrEMBL
    G5C9K3
    Related
    ENSHGLP00000023357.1, ENSHGLT00000023574.1
    Conserved Domains (1) summary
    cl12078
    Location:61 → 477
    p450; Cytochrome P450

RNA

  1. XR_002388667.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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