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Shc1 SHC adaptor protein 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101717434, updated on 11-Apr-2024

Summary

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Gene symbol
Shc1
Gene description
SHC adaptor protein 1
See related
Ensembl:ENSHGLG00000006430
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624885.1 (2511039..2520883)

NW_004624885.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene flavin adenine dinucleotide synthetase 1 Neighboring gene CDC28 protein kinase regulatory subunit 1B Neighboring gene pygopus family PHD finger 2 Neighboring gene PBX homeobox interacting protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624885 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SHC-transforming protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624885.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    2511039..2520883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021249359.1 → XP_021105018.1  SHC-transforming protein 1 isoform X5

    UniProtKB/TrEMBL
    G5BDE0
    Conserved Domains (2) summary
    cd09925
    Location:415 → 518
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:36 → 252
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  2. XM_021249356.1 → XP_021105015.1  SHC-transforming protein 1 isoform X1

    Conserved Domains (2) summary
    cd09925
    Location:525 → 628
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 362
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  3. XM_021249357.1 → XP_021105016.1  SHC-transforming protein 1 isoform X2

    Conserved Domains (2) summary
    cd09925
    Location:509 → 612
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 346
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  4. XM_021249358.1 → XP_021105017.1  SHC-transforming protein 1 isoform X3

    Conserved Domains (2) summary
    cd09925
    Location:496 → 599
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 333
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain

  5. XM_004871325.3 → XP_004871382.1  SHC-transforming protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A0P6K6U4, G5BDE0
    Related
    ENSHGLP00000008948.1, ENSHGLT00000009043.1
    Conserved Domains (2) summary
    cd09925
    Location:480 → 583
    SH2_SHC; Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC)
    cd01209
    Location:146 → 317
    PTB_Shc; Shc-like phosphotyrosine-binding (PTB) domain
Nucleotide Protein
Heading Accession and Version

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