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LOC101716577 tyrosine-protein kinase ZAP-70 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101716577, updated on 11-Apr-2024

Summary

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Gene symbol
LOC101716577
Gene description
tyrosine-protein kinase ZAP-70
See related
Ensembl:ENSHGLG00000004616
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Also known as
Zap70
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624749.1 (2893601..2901256)

NW_004624749.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 5B, mitochondrial Neighboring gene actin related protein 1B Neighboring gene transmembrane protein 131 Neighboring gene nucleophosmin pseudogene Neighboring gene uncharacterized LOC110349057

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624749 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ZAP-70
Names
zeta-chain (TCR) associated protein kinase 70kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624749.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    2893601..2901256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021258042.1 → XP_021113701.1  tyrosine-protein kinase ZAP-70

    UniProtKB/TrEMBL
    G5BMU3
    Related
    ENSHGLP00000006316.1, ENSHGLT00000006397.1
    Conserved Domains (3) summary
    cd09938
    Location:8 → 111
    SH2_N-SH2_Zap70_Syk_like; N-terminal Src homology 2 (SH2) domain found in Zeta-chain-associated protein kinase 70 (ZAP-70) and Spleen tyrosine kinase (Syk) proteins
    cd05115
    Location:330 → 598
    PTKc_Zap-70; Catalytic domain of the Protein Tyrosine Kinase, Zeta-chain-associated protein of 70kDa
    cl15255
    Location:152 → 256
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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