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Ksr2 kinase suppressor of ras 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101710530, updated on 8-Mar-2024

Summary

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Gene symbol
Ksr2
Gene description
kinase suppressor of ras 2
See related
Ensembl:ENSHGLG00000016442
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624747.1 (15492312..15931358)

NW_004624747.1Genomic Context describing neighboring genes Neighboring gene general transcription factor IIF subunit 1 pseudogene Neighboring gene signal recognition particle 19 kDa protein pseudogene Neighboring gene WD repeat and SOCS box containing 2 Neighboring gene replication factor C subunit 5 Neighboring gene glomulin-like Neighboring gene uncharacterized LOC110348898 Neighboring gene DCN1-like protein 4 pseudogene Neighboring gene nitric oxide synthase 1 Neighboring gene pre-B-cell leukemia transcription factor 2 pseudogene Neighboring gene uncharacterized LOC106009278 Neighboring gene F-box protein 21

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624747 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kinase suppressor of Ras 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624747.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    15492312..15931358
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013071743.2 → XP_012927197.1  kinase suppressor of Ras 2 isoform X1

    See identical proteins and their annotated locations for XP_012927197.1

    UniProtKB/TrEMBL
    G5AKT0
    Conserved Domains (4) summary
    cd00029
    Location:413 → 455
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd14153
    Location:665 → 934
    PK_KSR2; Pseudokinase domain of Kinase Suppressor of Ras 2
    pfam07714
    Location:666 → 928
    Pkinase_Tyr; Protein tyrosine kinase
    pfam13543
    Location:24 → 152
    KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

  2. XM_013071742.2 → XP_012927196.1  kinase suppressor of Ras 2 isoform X1

    See identical proteins and their annotated locations for XP_012927196.1

    UniProtKB/TrEMBL
    G5AKT0
    Conserved Domains (4) summary
    cd00029
    Location:413 → 455
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd14153
    Location:665 → 934
    PK_KSR2; Pseudokinase domain of Kinase Suppressor of Ras 2
    pfam07714
    Location:666 → 928
    Pkinase_Tyr; Protein tyrosine kinase
    pfam13543
    Location:24 → 152
    KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

  3. XM_004843700.3 → XP_004843757.1  kinase suppressor of Ras 2 isoform X3

    UniProtKB/TrEMBL
    G5AKT0
    Conserved Domains (4) summary
    cd00029
    Location:413 → 455
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd14153
    Location:663 → 932
    PK_KSR2; Pseudokinase domain of Kinase Suppressor of Ras 2
    pfam07714
    Location:664 → 926
    Pkinase_Tyr; Protein tyrosine kinase
    pfam13543
    Location:24 → 152
    KSR1-SAM; SAM like domain present in kinase suppressor RAS 1

  4. XM_013071744.2 → XP_012927198.1  kinase suppressor of Ras 2 isoform X2

    UniProtKB/TrEMBL
    G5AKT0
    Related
    ENSHGLP00000023060.1, ENSHGLT00000023275.1
    Conserved Domains (4) summary
    cd00029
    Location:413 → 455
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd14153
    Location:665 → 934
    PK_KSR2; Pseudokinase domain of Kinase Suppressor of Ras 2
    pfam07714
    Location:666 → 928
    Pkinase_Tyr; Protein tyrosine kinase
    pfam13543
    Location:24 → 152
    KSR1-SAM; SAM like domain present in kinase suppressor RAS 1
Nucleotide Protein
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