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Ddx5 DEAD-box helicase 5 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101707835, updated on 8-Mar-2024

Summary

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Gene symbol
Ddx5
Gene description
DEAD-box helicase 5
Locus tag
GW7_20873
See related
Ensembl:ENSHGLG00000001771
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624870.1 (206714..214264, complement)

NW_004624870.1Genomic Context describing neighboring genes Neighboring gene platelet and endothelial cell adhesion molecule 1 Neighboring gene mast cell immunoglobulin like receptor 1 Neighboring gene DNA polymerase gamma 2, accessory subunit Neighboring gene centrosomal protein 95 Neighboring gene uncharacterized LOC110346827 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene cytoplasmic protein NCK1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624870 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable ATP-dependent RNA helicase DDX5
Names
Putative ATP-dependent RNA helicase DDX5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624870.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    206714..214264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004870239.3 → XP_004870296.1  probable ATP-dependent RNA helicase DDX5

    See identical proteins and their annotated locations for XP_004870296.1

    UniProtKB/TrEMBL
    G5BVF2
    Related
    ENSHGLP00000002331.1, ENSHGLT00000002380.1
    Conserved Domains (4) summary
    cd00079
    Location:312 → 444
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:96 → 301
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    PTZ00110
    Location:6 → 507
    PTZ00110; helicase; Provisional
    pfam08061
    Location:552 → 584
    P68HR; P68HR (NUC004) repeat

  2. XM_004870241.3 → XP_004870298.1  probable ATP-dependent RNA helicase DDX5

    See identical proteins and their annotated locations for XP_004870298.1

    UniProtKB/TrEMBL
    G5BVF2
    Conserved Domains (4) summary
    cd00079
    Location:312 → 444
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:96 → 301
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    PTZ00110
    Location:6 → 507
    PTZ00110; helicase; Provisional
    pfam08061
    Location:552 → 584
    P68HR; P68HR (NUC004) repeat
Nucleotide Protein
Heading Accession and Version

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