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TIMP3 TIMP metallopeptidase inhibitor 3 [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101681298, updated on 19-Jun-2024

Summary

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Gene symbol
TIMP3
Gene description
TIMP metallopeptidase inhibitor 3
See related
Ensembl:ENSMPUG00000012384
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025421463.1 (10939843..10996364, complement)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569151.1 (8372247..8428774)

NW_025421463.1Genomic Context describing neighboring genes Neighboring gene LARGE xylosyl- and glucuronyltransferase 1 Neighboring gene small nucleolar RNA SNORA76 Neighboring gene U4 spliceosomal RNA Neighboring gene synapsin III Neighboring gene uncharacterized LOC106004888 Neighboring gene F-box protein 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De-novo transcriptome sequencing of a normalized cDNA pool from influenza infected ferrets. Camp JV, et al. PLoS One, 2012. PMID 22606336, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metalloproteinase inhibitor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025421463.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    10939843..10996364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004743089.3 → XP_004743146.1  metalloproteinase inhibitor 3

    See identical proteins and their annotated locations for XP_004743146.1

    UniProtKB/TrEMBL
    M3YLT3
    Related
    ENSMPUP00000012290.1
    Conserved Domains (1) summary
    cd03585
    Location:24 → 200
    NTR_TIMP; NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by ...
Nucleotide Protein
Heading Accession and Version

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