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HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [ Condylura cristata (star-nosed mole) ]

Gene ID: 101626744, updated on 8-Mar-2024

Summary

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Gene symbol
HMGCS2
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Condylura cristata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Condylura
Orthologs
human mouse all
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Genomic context

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See HMGCS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
101 current ConCri1.0 (GCF_000260355.1) Unplaced Scaffold NW_004567127.1 (2500690..2514736)

NW_004567127.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase domain 30 Neighboring gene regenerating family member 4 Neighboring gene phosphoglycerate dehydrogenase Neighboring gene zinc finger protein 697

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004567127.1 Unplaced Scaffold Reference ConCri1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Condylura cristata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ConCri1.0

Genomic

  1. NW_004567127.1 Reference ConCri1.0

    Range
    2500690..2514736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004689479.2 → XP_004689536.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X1

    Conserved Domains (3) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:53 → 223
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:224 → 506
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_012730055.1 → XP_012585509.1  hydroxymethylglutaryl-CoA synthase, mitochondrial isoform X2

    Conserved Domains (3) summary
    TIGR01833
    Location:50 → 464
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam08540
    Location:187 → 464
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
    cl09938
    Location:53 → 187
    cond_enzymes; Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the ...
Nucleotide Protein
Heading Accession and Version

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