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SQLE squalene epoxidase [ Sorex araneus (European shrew) ]

Gene ID: 101556612, updated on 8-Mar-2024

Summary

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Gene symbol
SQLE
Gene description
squalene epoxidase
See related
EnsemblRapid:ENSSARG00000008598
Gene type
protein coding
RefSeq status
MODEL
Organism
Sorex araneus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Soricinae; Sorex
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_04 current mSorAra2.pri (GCF_027595985.1) 2 NC_073303.1 (103416779..103438069, complement)
101 previous assembly SorAra2.0 (GCF_000181275.1) Unplaced Scaffold NW_004545883.1 (1104429..1125726, complement)

Chromosome 2 - NC_073303.1Genomic Context describing neighboring genes Neighboring gene NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase Neighboring gene ubiquitin-40S ribosomal protein S27a-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene WASH complex subunit 5 Neighboring gene 10 kDa heat shock protein, mitochondrial-like Neighboring gene U8 small nucleolar RNA Neighboring gene zinc finger protein 572

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables squalene monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene monooxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027595985.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSorAra2.pri

Genomic

  1. NC_073303.1 Reference mSorAra2.pri

    Range
    103416779..103438069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004607632.2 → XP_004607689.1  squalene monooxygenase isoform X2

    Related
    ENSSARP00000007781.2, ENSSART00000008601.2
    Conserved Domains (2) summary
    COG0654
    Location:126 → 501
    UbiH; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]
    cl21454
    Location:278 → 549
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_055128510.1 → XP_054984485.1  squalene monooxygenase isoform X1

    Related
    ENSSARP00000025793.1, ENSSART00000024927.1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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