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ESR2 estrogen receptor 2 [ Ceratotherium simum simum (southern white rhinoceros) ]

Gene ID: 101400242, updated on 19-Jun-2024

Summary

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Gene symbol
ESR2
Gene description
estrogen receptor 2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ceratotherium simum simum (sub-species: simum)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Rhinocerotidae; Ceratotherium
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
101 current CerSimSim1.0 (GCF_000283155.1) Unplaced Scaffold NW_004454173.1 (10935874..10992484, complement)

NW_004454173.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106801235 Neighboring gene spectrin repeat containing nuclear envelope protein 2 Neighboring gene coiled-coil domain-containing protein 170-like Neighboring gene methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004454173.1 Unplaced Scaffold Reference CerSimSim1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Activation of southern white rhinoceros (Ceratotherium simum simum) estrogen receptors by phytoestrogens: potential role in the reproductive failure of captive-born females? Tubbs C, et al. Endocrinology, 2012 Mar. PMID 22253418, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to estradiol stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in estrogen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
estrogen receptor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001279251.1 → NP_001266180.1  estrogen receptor beta

    See identical proteins and their annotated locations for NP_001266180.1

    Status: PROVISIONAL

    Source sequence(s)
    JN997453
    UniProtKB/TrEMBL
    H6VYN7
    Conserved Domains (3) summary
    cd06949
    Location:282 → 517
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:163 → 244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:35 → 141
    ERbeta_N; Estrogen receptor beta

RefSeqs of Annotated Genomes: Ceratotherium simum simum Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CerSimSim1.0 Primary Assembly

Genomic

  1. NW_004454173.1 Reference CerSimSim1.0 Primary Assembly

    Range
    10935874..10992484 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014784228.1 → XP_014639714.1  estrogen receptor beta isoform X1

    Conserved Domains (3) summary
    cd06949
    Location:282 → 517
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:163 → 244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:35 → 141
    ERbeta_N; Estrogen receptor beta
Nucleotide Protein
Heading Accession and Version

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