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HIF3A hypoxia inducible factor 3 subunit alpha [ Odobenus rosmarus divergens (Pacific walrus) ]

Gene ID: 101372866, updated on 8-Mar-2024

Summary

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Gene symbol
HIF3A
Gene description
hypoxia inducible factor 3 subunit alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Odobenus rosmarus divergens (sub-species: divergens)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae; Odobenus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Oros_1.0 (GCF_000321225.1) Unplaced Scaffold NW_004450389.1 (1342689..1370050, complement)

NW_004450389.1Genomic Context describing neighboring genes Neighboring gene PNMA family member 8A Neighboring gene protein phosphatase 5 catalytic subunit Neighboring gene uncharacterized LOC101368713 Neighboring gene peptidoglycan recognition protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004450389.1 Unplaced Scaffold Reference Oros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypoxia-inducible factor 3-alpha
Names
hypoxia inducible factor 3 alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odobenus rosmarus divergens Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oros_1.0 Primary Assembly

Genomic

  1. NW_004450389.1 Reference Oros_1.0 Primary Assembly

    Range
    1342689..1370050 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004400953.1 → XP_004401010.1  hypoxia-inducible factor 3-alpha isoform X2

    UniProtKB/TrEMBL
    A0A2U3VZI5
    Conserved Domains (3) summary
    cd00130
    Location:172 → 269
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam11413
    Location:411 → 440
    HIF-1; Hypoxia-inducible factor-1
    pfam14598
    Location:172 → 277
    PAS_11; PAS domain

  2. XM_004400951.2 → XP_004401008.1  hypoxia-inducible factor 3-alpha isoform X1

    UniProtKB/TrEMBL
    A0A2U3VZN4
    Conserved Domains (4) summary
    cd00083
    Location:13 → 68
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:241 → 338
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam11413
    Location:480 → 509
    HIF-1; Hypoxia-inducible factor-1
    pfam14598
    Location:241 → 346
    PAS_11; PAS domain

  3. XM_004400952.1 → XP_004401009.1  hypoxia-inducible factor 3-alpha isoform X3

    UniProtKB/TrEMBL
    A0A2U3VZL8
    Conserved Domains (3) summary
    cd00130
    Location:187 → 284
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam11413
    Location:426 → 455
    HIF-1; Hypoxia-inducible factor-1
    pfam14598
    Location:187 → 292
    PAS_11; PAS domain
Nucleotide Protein
Heading Accession and Version

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