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BACE2 beta-secretase 2 [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101327239, updated on 8-Mar-2024

Summary

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Gene symbol
BACE2
Gene description
beta-secretase 2
See related
EnsemblRapid:ENSTTRG00000007037
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 4 NC_047037.1 (139761027..139848495)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017844625.1 (3520527..3601634, complement)

Chromosome 4 - NC_047037.1Genomic Context describing neighboring genes Neighboring gene DS cell adhesion molecule Neighboring gene U6 spliceosomal RNA Neighboring gene THAP domain-containing protein 6-like Neighboring gene uncharacterized LOC109547892 Neighboring gene interferon-induced GTP-binding protein Mx2-like Neighboring gene FAM3 metabolism regulating signaling molecule B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-secretase 2
Names
beta-site APP-cleaving enzyme 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047037.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    139761027..139848495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019923162.2 → XP_019778721.1  beta-secretase 2

    UniProtKB/TrEMBL
    A0A2U4ACU3
    Related
    ENSTTRP00000006672.2, ENSTTRT00000007054.2
    Conserved Domains (1) summary
    cd05473
    Location:85 → 446
    beta_secretase_like; Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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