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NTRK1 neurotrophic receptor tyrosine kinase 1 [ Tursiops truncatus (common bottlenose dolphin) ]

Gene ID: 101316123, updated on 11-Apr-2024

Summary

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Gene symbol
NTRK1
Gene description
neurotrophic receptor tyrosine kinase 1
See related
EnsemblRapid:ENSTTRG00000014516
Gene type
protein coding
RefSeq status
MODEL
Organism
Tursiops truncatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
102 current mTurTru1.mat.Y (GCF_011762595.1) 1 NC_047034.1 (70857033..70876235, complement)
101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017842185.1 (6714109..6717678)

Chromosome 1 - NC_047034.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 71 Neighboring gene platelet endothelial aggregation receptor 1 Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene insulin receptor related receptor Neighboring gene SH2 domain containing 2A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nerve growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nerve growth factor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity nerve growth factor receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mTurTru1.mat.Y Primary Assembly

Genomic

  1. NC_047034.1 Reference mTurTru1.mat.Y Primary Assembly

    Range
    70857033..70876235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033857030.1 → XP_033712921.1  high affinity nerve growth factor receptor

    UniProtKB/TrEMBL
    A0A6J3RDS8
    Related
    ENSTTRP00000029505.1, ENSTTRT00000030877.1
    Conserved Domains (6) summary
    cd05092
    Location:529 → 808
    PTKc_TrkA; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A
    sd00031
    Location:94 → 118
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:118 → 176
    LRR_8; Leucine rich repeat
    pfam16920
    Location:177 → 218
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cd04971
    Location:311 → 405
    IgI_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB, and TrkC; member of the I-set of Ig superfamily (IgSF) domains
    cd04972
    Location:221 → 308
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB, and TrkC
Nucleotide Protein
Heading Accession and Version

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