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CIT citron rho-interacting serine/threonine kinase [ Orcinus orca (killer whale) ]

Gene ID: 101288927, updated on 8-Mar-2024

Summary

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Gene symbol
CIT
Gene description
citron rho-interacting serine/threonine kinase
See related
EnsemblRapid:ENSOORG00010014440
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 15 NC_064573.1 (79761547..79933447, complement)

Chromosome 15 - NC_064573.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 60 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene transmembrane protein 233 Neighboring gene protein kinase AMP-activated non-catalytic subunit beta 1 Neighboring gene uncharacterized LOC125961291 Neighboring gene acyl-CoA dehydrogenase family member 10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064573.1 Chromosome 15 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
citron Rho-interacting kinase
Names
citron (rho-interacting, serine/threonine kinase 21)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064573.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    79761547..79933447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033399983.2 → XP_033255874.1  citron Rho-interacting kinase isoform X5

    Related
    ENSOORP00010018707.1, ENSOORT00010021503.1
    Conserved Domains (5) summary
    smart00036
    Location:1578 → 1874
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:481 → 1283
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:95 → 422
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1429 → 1548
    PH; PH domain
    cd20814
    Location:1344 → 1399
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  2. XM_033399980.2 → XP_033255871.1  citron Rho-interacting kinase isoform X4

    Conserved Domains (5) summary
    smart00036
    Location:1620 → 1916
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:474 → 1320
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:95 → 422
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1471 → 1590
    PH; PH domain
    cd20814
    Location:1386 → 1441
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  3. XM_004276745.4 → XP_004276793.1  citron Rho-interacting kinase isoform X3

    Related
    ENSOORP00010018706.1, ENSOORT00010021502.1
    Conserved Domains (6) summary
    smart00036
    Location:1635 → 1931
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:102 → 360
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1196
    Location:474 → 1335
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00029
    Location:1405 → 1453
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd05601
    Location:95 → 422
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1486 → 1605
    PH; PH domain

  4. XM_033399979.2 → XP_033255870.1  citron Rho-interacting kinase isoform X2

    Conserved Domains (5) summary
    smart00036
    Location:1620 → 1916
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:474 → 1320
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:95 → 422
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1471 → 1590
    PH; PH domain
    cd20814
    Location:1386 → 1441
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins

  5. XM_033399977.2 → XP_033255868.1  citron Rho-interacting kinase isoform X1

    Conserved Domains (5) summary
    smart00036
    Location:1635 → 1931
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    COG1196
    Location:474 → 1335
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd05601
    Location:95 → 422
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1486 → 1605
    PH; PH domain
    cd20814
    Location:1401 → 1456
    CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
Nucleotide Protein
Heading Accession and Version

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