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TFPI tissue factor pathway inhibitor [ Orcinus orca (killer whale) ]

Gene ID: 101287826, updated on 8-Mar-2024

Summary

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Gene symbol
TFPI
Gene description
tissue factor pathway inhibitor
See related
EnsemblRapid:ENSOORG00010011751
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See TFPI in Genome Data Viewer
Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 7 NC_064565.1 (74272522..74355260, complement)

Chromosome 7 - NC_064565.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC125964992 Neighboring gene calcitonin receptor like receptor Neighboring gene pancreatic progenitor cell differentiation and proliferation factor-like Neighboring gene U6 spliceosomal RNA Neighboring gene GULP PTB domain containing engulfment adaptor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064565.1 Chromosome 7 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tissue factor pathway inhibitor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064565.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    74272522..74355260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049712249.1 → XP_049568206.1  tissue factor pathway inhibitor isoform X1

  2. XM_033400254.2 → XP_033256145.1  tissue factor pathway inhibitor isoform X1

    Conserved Domains (2) summary
    cd00109
    Location:125 → 177
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:53 → 104
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

  3. XM_004276920.3 → XP_004276968.1  tissue factor pathway inhibitor isoform X1

    Related
    ENSOORP00010014908.1, ENSOORT00010017328.1
    Conserved Domains (2) summary
    cd00109
    Location:125 → 177
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:53 → 104
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

  4. XM_033400256.2 → XP_033256147.1  tissue factor pathway inhibitor isoform X2

    Related
    ENSOORP00010014905.1, ENSOORT00010017325.1
    Conserved Domains (2) summary
    cd00109
    Location:125 → 177
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:53 → 104
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

RNA

  1. XR_007478393.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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