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BMP4 bone morphogenetic protein 4 [ Orcinus orca (killer whale) ]

Gene ID: 101278431, updated on 8-Mar-2024

Summary

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Gene symbol
BMP4
Gene description
bone morphogenetic protein 4
See related
EnsemblRapid:ENSOORG00010014689
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See BMP4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 2 NC_064560.1 (154913967..154928091, complement)

Chromosome 2 - NC_064560.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L15-like Neighboring gene 40S ribosomal protein S3a-like Neighboring gene V-type proton ATPase subunit e 1-like Neighboring gene cyclin dependent kinase inhibitor 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064560.1 Chromosome 2 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables BMP receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bone morphogenetic protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064560.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    154913967..154928091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_049706260.1 → XP_049562217.1  bone morphogenetic protein 4

  2. XM_033404754.2 → XP_033260645.1  bone morphogenetic protein 4

    Conserved Domains (2) summary
    cd19391
    Location:302 → 408
    TGF_beta_BMP4_BMP2B; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 4 (BMP-4) and similar proteins
    pfam00688
    Location:41 → 275
    TGFb_propeptide; TGF-beta propeptide

  3. XM_049706259.1 → XP_049562216.1  bone morphogenetic protein 4

    Related
    ENSOORP00010019022.1, ENSOORT00010021827.1

  4. XM_004279343.3 → XP_004279391.1  bone morphogenetic protein 4

    See identical proteins and their annotated locations for XP_004279391.1

    Conserved Domains (2) summary
    cd19391
    Location:302 → 408
    TGF_beta_BMP4_BMP2B; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 4 (BMP-4) and similar proteins
    pfam00688
    Location:41 → 275
    TGFb_propeptide; TGF-beta propeptide
Nucleotide Protein
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