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PKD2 polycystin 2, transient receptor potential cation channel [ Orcinus orca (killer whale) ]

Gene ID: 101269935, updated on 8-Mar-2024

Summary

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Gene symbol
PKD2
Gene description
polycystin 2, transient receptor potential cation channel
See related
EnsemblRapid:ENSOORG00010007222
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
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Genomic context

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See PKD2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 4 NC_064562.1 (9334907..9384140)

Chromosome 4 - NC_064562.1Genomic Context describing neighboring genes Neighboring gene matrix extracellular phosphoglycoprotein Neighboring gene secreted phosphoprotein 1 Neighboring gene ATP binding cassette subfamily G member 2 (JR blood group) Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1K

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064562.1 Chromosome 4 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of mechanical stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
polycystin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064562.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    9334907..9384140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004266134.3 → XP_004266182.1  polycystin-2 isoform X1

    Related
    ENSOORP00010008741.1, ENSOORT00010010497.1
    Conserved Domains (2) summary
    pfam08016
    Location:272 → 692
    PKD_channel; Polycystin cation channel
    cl08302
    Location:737 → 783
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  2. XM_049709016.1 → XP_049564973.1  polycystin-2 isoform X2

Nucleotide Protein
Heading Accession and Version

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