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irs2b insulin receptor substrate 2b [ Oryzias latipes (Japanese medaka) ]

Gene ID: 101162408, updated on 8-Mar-2024

Summary

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Gene symbol
irs2b
Gene description
insulin receptor substrate 2b
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryzias latipes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
Also known as
irs2
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 21
Exon count:
2
Annotation release Status Assembly Chr Location
103 current ASM223467v1 (GCF_002234675.1) 21 NC_019879.2 (25784846..25797913, complement)
102 previous assembly ASM31367v1 (GCF_000313675.1) 21 NC_019879.1 (25887462..25898467, complement)

Chromosome 21 - NC_019879.2Genomic Context describing neighboring genes Neighboring gene TNF superfamily member 13b Neighboring gene myosin XVI Neighboring gene collagen, type IV, alpha 1 Neighboring gene collagen, type IV, alpha 2 Neighboring gene uncharacterized LOC105358762

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables insulin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin receptor substrate 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM223467v1 Primary Assembly

Genomic

  1. NC_019879.2 Reference ASM223467v1 Primary Assembly

    Range
    25784846..25797913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004082003.4 → XP_004082051.2  insulin receptor substrate 2

    UniProtKB/TrEMBL
    A0A3P9HN67, H2MUQ0
    Conserved Domains (3) summary
    cd01204
    Location:155 → 258
    PTB_IRS; Insulin receptor substrate phosphotyrosine-binding domain (PTBi)
    cd01257
    Location:19 → 124
    PH_IRS; Insulin receptor substrate (IRS) pleckstrin homology (PH) domain
    pfam00169
    Location:21 → 121
    PH; PH domain
Nucleotide Protein
Heading Accession and Version

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