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CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 [ Ovis aries (sheep) ]

Gene ID: 101122727, updated on 8-Mar-2024

Summary

Gene symbol
CASTOR1
Gene description
cytosolic arginine sensor for mTORC1 subunit 1
See related
EnsemblRapid:ENSOARG00020014862
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
GATSL3
Orthologs
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Genomic context

Location:
chromosome: 17
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 17 NC_056070.1 (69303510..69308189, complement)

Chromosome 17 - NC_056070.1Genomic Context describing neighboring genes Neighboring gene LIF interleukin 6 family cytokine Neighboring gene oncostatin M Neighboring gene TBC1 domain family member 10A Neighboring gene splicing factor 3a subunit 1

Genomic regions, transcripts, and products

Genomic Sequence:
NC_056070.1 Chromosome 17 Reference ARS-UI_Ramb_v3.0 Primary Assembly

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arginine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-arginine IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cytosolic arginine sensor for mTORC1 subunit 1
Names
GATS protein like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056070.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    69303510..69308189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042234819.2XP_042090753.1  cytosolic arginine sensor for mTORC1 subunit 1 isoform X3

  2. XM_042234821.2XP_042090755.1  cytosolic arginine sensor for mTORC1 subunit 1 isoform X4

    Conserved Domains (1) summary
    cl09141
    Location:198256
    ACT; ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme
  3. XM_027956759.3XP_027812560.1  cytosolic arginine sensor for mTORC1 subunit 1 isoform X1

  4. XM_015101711.4XP_014957197.2  cytosolic arginine sensor for mTORC1 subunit 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P3YMK0
    Related
    ENSOARP00020018911.2, ENSOART00020022805.2
    Conserved Domains (2) summary
    pfam13840
    Location:259323
    ACT_7; ACT domain
    pfam18700
    Location:969
    Castor1_N; Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain