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ASB8 ankyrin repeat and SOCS box containing 8 [ Ovis aries (sheep) ]

Gene ID: 101108118, updated on 8-Mar-2024

Summary

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Gene symbol
ASB8
Gene description
ankyrin repeat and SOCS box containing 8
See related
EnsemblRapid:ENSOARG00020002188
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 3 NC_056056.1 (138438914..138447453)

Chromosome 3 - NC_056056.1Genomic Context describing neighboring genes Neighboring gene ERO1-like protein alpha Neighboring gene coiled-coil domain containing 184 Neighboring gene phosphofructokinase, muscle Neighboring gene SUMO specific peptidase 1 Neighboring gene collagen type II alpha 1 chain

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056056.1 Chromosome 3 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ankyrin repeat and SOCS box protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056056.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    138438914..138447453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042246794.1 → XP_042102728.1  ankyrin repeat and SOCS box protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TBD0, W5QDB9
    Conserved Domains (3) summary
    PHA02876
    Location:26 → 215
    PHA02876; ankyrin repeat protein; Provisional
    cd03727
    Location:245 → 286
    SOCS_ASB8; SOCS (suppressors of cytokine signaling) box of ASB8-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Human ASB8 is highly transcribed in skeletal muscle and in lung carcinoma cell lines. The ...
    sd00045
    Location:56 → 83
    ANK; ANK repeat [structural motif]

  2. XM_060412686.1 → XP_060268669.1  ankyrin repeat and SOCS box protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A6P3TBD0, W5QDB9

  3. XM_012174379.4 → XP_012029769.1  ankyrin repeat and SOCS box protein 8 isoform X1

    See identical proteins and their annotated locations for XP_012029769.1

    UniProtKB/TrEMBL
    A0A6P3TBD0, W5QDB9
    Related
    ENSOARP00020056436.1, ENSOART00020068867.1
    Conserved Domains (3) summary
    PHA02876
    Location:26 → 215
    PHA02876; ankyrin repeat protein; Provisional
    cd03727
    Location:245 → 286
    SOCS_ASB8; SOCS (suppressors of cytokine signaling) box of ASB8-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Human ASB8 is highly transcribed in skeletal muscle and in lung carcinoma cell lines. The ...
    sd00045
    Location:56 → 83
    ANK; ANK repeat [structural motif]

  4. XM_004006405.5 → XP_004006454.1  ankyrin repeat and SOCS box protein 8 isoform X1

    See identical proteins and their annotated locations for XP_004006454.1

    UniProtKB/TrEMBL
    A0A6P3TBD0, W5QDB9
    Conserved Domains (3) summary
    PHA02876
    Location:26 → 215
    PHA02876; ankyrin repeat protein; Provisional
    cd03727
    Location:245 → 286
    SOCS_ASB8; SOCS (suppressors of cytokine signaling) box of ASB8-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Human ASB8 is highly transcribed in skeletal muscle and in lung carcinoma cell lines. The ...
    sd00045
    Location:56 → 83
    ANK; ANK repeat [structural motif]

  5. XM_042246795.1 → XP_042102729.1  ankyrin repeat and SOCS box protein 8 isoform X2

    Conserved Domains (3) summary
    cd03727
    Location:184 → 225
    SOCS_ASB8; SOCS (suppressors of cytokine signaling) box of ASB8-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Human ASB8 is highly transcribed in skeletal muscle and in lung carcinoma cell lines. The ...
    sd00045
    Location:24 → 54
    ANK; ANK repeat [structural motif]
    cl39094
    Location:8 → 120
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein Strain
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