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PTAFR platelet activating factor receptor [ Ovis aries (sheep) ]

Gene ID: 101104560, updated on 6-Jun-2024

Summary

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Gene symbol
PTAFR
Gene description
platelet activating factor receptor
See related
EnsemblRapid:ENSOARG00020035955
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
PAFR
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (238909652..238953311)

Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene ATP synthase inhibitory factor subunit 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C8 Neighboring gene translationally-controlled tumor protein-like Neighboring gene large ribosomal subunit protein eL39-like Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of platelet-activating factor in pulmonary vascular remodeling associated with chronic high altitude hypoxia in ovine fetal lambs. Bixby CE, et al. Am J Physiol Lung Cell Mol Physiol, 2007 Dec. PMID 17951313
  2. Oxygen-dependent PAF receptor binding and intracellular signaling in ovine fetal pulmonary vascular smooth muscle. Ibe BO, et al. Am J Physiol Lung Cell Mol Physiol, 2005 May. PMID 15618453

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These data demonstrate that exposure of ovine fetuses to high altitude hypoxia will result in significant upregulation of PAF synthesis, PAF-R expression, and PAF-R-mediated effects in pulmonary arteries.
    Title: Role of platelet-activating factor in pulmonary vascular remodeling associated with chronic high altitude hypoxia in ovine fetal lambs.
  2. fetal hypoxic environment facilitates PAF-r binding and signaling, thereby promoting PAF-mediated pulmonary vasoconstriction
    Title: Oxygen-dependent PAF receptor binding and intracellular signaling in ovine fetal pulmonary vascular smooth muscle.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled purinergic nucleotide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables platelet activating factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
platelet-activating factor receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    238909652..238953311
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060411425.1 → XP_060267408.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Related
    ENSOARP00020050818.1, ENSOART00020080322.1

  2. XM_042245088.2 → XP_042101022.1  platelet-activating factor receptor isoform X2

    UniProtKB/TrEMBL
    W5QF06
    Related
    ENSOARP00020048240.1, ENSOART00020051529.1
    Conserved Domains (1) summary
    cd15147
    Location:38 → 326
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_060411421.1 → XP_060267404.1  platelet-activating factor receptor isoform X1

    UniProtKB/TrEMBL
    W5QF06

  4. XM_042245085.2 → XP_042101019.1  platelet-activating factor receptor isoform X1

    UniProtKB/TrEMBL
    W5QF06
    Conserved Domains (1) summary
    cd15147
    Location:95 → 383
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_042245092.2 → XP_042101026.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Conserved Domains (1) summary
    cd15147
    Location:27 → 315
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_060411420.1 → XP_060267403.1  platelet-activating factor receptor isoform X1

    UniProtKB/TrEMBL
    W5QF06

  7. XM_027965425.3 → XP_027821226.2  platelet-activating factor receptor isoform X1

    UniProtKB/TrEMBL
    W5QF06
    Conserved Domains (1) summary
    cd15147
    Location:95 → 383
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  8. XM_060411424.1 → XP_060267407.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Related
    ENSOARP00020042318.1, ENSOART00020053357.1

  9. XM_060411423.1 → XP_060267406.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Related
    ENSOARP00020042678.1, ENSOART00020062388.1

  10. XM_042245093.2 → XP_042101027.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Conserved Domains (1) summary
    cd15147
    Location:27 → 315
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  11. XM_042245094.2 → XP_042101028.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Conserved Domains (1) summary
    cd15147
    Location:27 → 315
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  12. XM_042245089.2 → XP_042101023.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Related
    ENSOARP00020036121.1, ENSOART00020057366.1
    Conserved Domains (1) summary
    cd15147
    Location:27 → 315
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  13. XM_042245087.2 → XP_042101021.1  platelet-activating factor receptor isoform X1

    UniProtKB/TrEMBL
    W5QF06
    Conserved Domains (1) summary
    cd15147
    Location:95 → 383
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  14. XM_042245091.2 → XP_042101025.1  platelet-activating factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A836AMU0, W5QF06
    Related
    ENSOARP00020059134.1, ENSOART00020067254.1
    Conserved Domains (1) summary
    cd15147
    Location:27 → 315
    7tmA_PAFR; platelet-activating factor receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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