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SKI SKI proto-oncogene [ Felis catus (domestic cat) ]

Gene ID: 101088346, updated on 17-Aug-2024

Summary

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Official Symbol
SKI
Official Full Name
SKI proto-oncogene
Primary source
VGNC:VGNC:80357
See related
EnsemblRapid:ENSFCTG00005015484
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: C1
Exon count:
7
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) C1 NC_058375.1 (1051363..1121199)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) C1 NC_018730.3 (1053132..1122863)

Chromosome C1 - NC_058375.1Genomic Context describing neighboring genes Neighboring gene collagen alpha-2(I) chain Neighboring gene translation initiation factor IF-2-like Neighboring gene FA core complex associated protein 20 Neighboring gene uncharacterized LOC109502028 Neighboring gene uncharacterized LOC102901119 Neighboring gene MORN repeat containing 1 Neighboring gene retention in endoplasmic reticulum sorting receptor 1 Neighboring gene peroxisomal biogenesis factor 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ski oncogene
Names
v-ski avian sarcoma viral oncogene homolog
v-ski sarcoma viral oncogene homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058375.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    1051363..1121199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023257965.2 → XP_023113733.2  ski oncogene isoform X1

    UniProtKB/TrEMBL
    M3X092
    Conserved Domains (2) summary
    smart01046
    Location:217 → 312
    c-SKI_SMAD_bind; c-SKI Smad4 binding domain
    TIGR02168
    Location:543 → 714
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_023257967.2 → XP_023113735.2  ski oncogene isoform X3

    UniProtKB/TrEMBL
    M3X092
    Related
    ENSFCTP00005031537.1, ENSFCTT00005044257.1
    Conserved Domains (2) summary
    smart01046
    Location:217 → 312
    c-SKI_SMAD_bind; c-SKI Smad4 binding domain
    TIGR02168
    Location:541 → 712
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. XM_023257966.2 → XP_023113734.2  ski oncogene isoform X2

    UniProtKB/TrEMBL
    M3X092
    Related
    ENSFCTP00005031447.1, ENSFCTT00005044148.1
    Conserved Domains (2) summary
    smart01046
    Location:217 → 312
    c-SKI_SMAD_bind; c-SKI Smad4 binding domain
    TIGR02168
    Location:542 → 713
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  4. XM_023257968.2 → XP_023113736.2  ski oncogene isoform X4

    UniProtKB/TrEMBL
    M3X092
    Conserved Domains (2) summary
    smart01046
    Location:217 → 312
    c-SKI_SMAD_bind; c-SKI Smad4 binding domain
    TIGR02168
    Location:540 → 711
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein
Heading Accession and Version

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