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ABCB8 ATP binding cassette subfamily B member 8 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100974982, updated on 8-Mar-2024

Summary

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Gene symbol
ABCB8
Gene description
ATP binding cassette subfamily B member 8
See related
Ensembl:ENSPPAG00000031904
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 6 NC_073255.2 (187449585..187467478)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 7 NC_073256.1 (39459849..39480013)

Chromosome 6 - NC_073255.2Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel subfamily H member 2 Neighboring gene nitric oxide synthase 3 Neighboring gene autophagy related 9B Neighboring gene acid sensing ion channel subunit 3 Neighboring gene cyclin dependent kinase 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitochondrial potassium channel ATP-binding subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073255.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    187449585..187467478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003815061.4 → XP_003815109.1  mitochondrial potassium channel ATP-binding subunit isoform X1

    UniProtKB/TrEMBL
    A0A2R9AK50, A0A2R9AS88
    Related
    ENSPPAP00000017729.1
    Conserved Domains (3) summary
    cd03249
    Location:455 → 693
    ABC_MTABC3_MDL1_MDL2; ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins
    COG1132
    Location:148 → 696
    MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
    pfam00664
    Location:145 → 408
    ABC_membrane; ABC transporter transmembrane region

  2. XM_008967941.4 → XP_008966189.2  mitochondrial potassium channel ATP-binding subunit isoform X2

    UniProtKB/TrEMBL
    A0A2R9AK50
    Conserved Domains (1) summary
    COG1132
    Location:103 → 662
    MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]

  3. XM_034965254.3 → XP_034821145.1  mitochondrial potassium channel ATP-binding subunit isoform X4

    UniProtKB/TrEMBL
    A0A2R9AK50
    Conserved Domains (2) summary
    cd18574
    Location:145 → 428
    ABC_6TM_ABCB8_like; Six-transmembrane helical domain (6-TMD) of ATP-binding cassette transporter subfamily B member 8, mitochondrial, and similar proteins
    cl38936
    Location:455 → 589
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_034965253.3 → XP_034821144.1  mitochondrial potassium channel ATP-binding subunit isoform X3

    UniProtKB/TrEMBL
    A0A2R9AK45
    Conserved Domains (1) summary
    COG1132
    Location:49 → 608
    MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
Nucleotide Protein
Heading Accession and Version

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