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GAD1 glutamate decarboxylase 1 [ Otolemur garnettii (small-eared galago) ]

Gene ID: 100957491, updated on 8-Mar-2024

Summary

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Gene symbol
GAD1
Gene description
glutamate decarboxylase 1
See related
Ensembl:ENSOGAG00000016613
Gene type
protein coding
RefSeq status
MODEL
Organism
Otolemur garnettii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
Orthologs
human mouse all
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Genomic context

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See GAD1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852582.1 (1288645..1331043)

NW_003852582.1Genomic Context describing neighboring genes Neighboring gene Sp5 transcription factor Neighboring gene U5 spliceosomal RNA Neighboring gene glutamate rich 2 Neighboring gene small nuclear ribonucleoprotein-associated protein N pseudogene Neighboring gene golgi reassembly stacking protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_003852582 Unplaced Scaffold Reference OtoGar3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glutamate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in gamma-aminobutyric acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutamate decarboxylase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OtoGar3

Genomic

  1. NW_003852582.1 Reference OtoGar3

    Range
    1288645..1331043
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003800861.2 → XP_003800909.1  glutamate decarboxylase 1 isoform X1

    UniProtKB/TrEMBL
    H0XFR7
    Related
    ENSOGAP00000014872.2, ENSOGAT00000016619.2
    Conserved Domains (1) summary
    pfam00282
    Location:144 → 518
    Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

  2. XM_012812082.1 → XP_012667536.1  glutamate decarboxylase 1 isoform X2

    Conserved Domains (1) summary
    cl18945
    Location:144 → 213
    AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
Nucleotide Protein
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