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BRWD3 bromodomain and WD repeat domain containing 3 [ Sarcophilus harrisii (Tasmanian devil) ]

Gene ID: 100915897, updated on 8-Mar-2024

Summary

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Gene symbol
BRWD3
Gene description
bromodomain and WD repeat domain containing 3
See related
Ensembl:ENSSHAG00000017788
Gene type
protein coding
RefSeq status
MODEL
Organism
Sarcophilus harrisii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
40
Annotation release Status Assembly Chr Location
103 current mSarHar1.11 (GCF_902635505.1) X NC_045432.1 (58173869..58299005, complement)
102 previous assembly Devil_ref v7.0 (GCF_000189315.1) X Unlocalized Scaffold NW_003849618.1 (2982155..3092877, complement)

Chromosome X - NC_045432.1Genomic Context describing neighboring genes Neighboring gene T-box transcription factor 22 Neighboring gene charged multivesicular body protein 1b-2 Neighboring gene terminal nucleotidyltransferase 5D Neighboring gene uncharacterized LOC111721612 Neighboring gene high mobility group nucleosome binding domain 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bromodomain and WD repeat-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mSarHar1.11 Primary Assembly

Genomic

  1. NC_045432.1 Reference mSarHar1.11 Primary Assembly

    Range
    58173869..58299005 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031944752.1 → XP_031800612.1  bromodomain and WD repeat-containing protein 3 isoform X5

    UniProtKB/TrEMBL
    G3WZX2
    Related
    ENSSHAP00000020977.2, ENSSHAT00000021147.2
    Conserved Domains (4) summary
    cd05529
    Location:1133 → 1245
    Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
    cd00200
    Location:175 → 496
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:186 → 223
    7WD40; WD40 repeat [structural motif]
    cl02556
    Location:1314 → 1427
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  2. XM_031944750.1 → XP_031800610.1  bromodomain and WD repeat-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    G3WZX2
    Conserved Domains (4) summary
    cd05529
    Location:961 → 1073
    Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
    cd00200
    Location:3 → 324
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:14 → 51
    7WD40; WD40 repeat [structural motif]
    cl02556
    Location:1126 → 1209
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  3. XM_023507027.2 → XP_023362795.1  bromodomain and WD repeat-containing protein 3 isoform X4

    UniProtKB/TrEMBL
    G3WZX2
    Conserved Domains (4) summary
    cd05529
    Location:961 → 1073
    Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
    cd00200
    Location:3 → 324
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:14 → 51
    7WD40; WD40 repeat [structural motif]
    cl02556
    Location:1142 → 1172
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  4. XM_023507026.2 → XP_023362794.1  bromodomain and WD repeat-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    G3WZX2
    Conserved Domains (4) summary
    cd05529
    Location:961 → 1073
    Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
    cd00200
    Location:3 → 324
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:14 → 51
    7WD40; WD40 repeat [structural motif]
    cl02556
    Location:1142 → 1204
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  5. XM_023507025.2 → XP_023362793.1  bromodomain and WD repeat-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    G3WZX2
    Conserved Domains (4) summary
    cd05529
    Location:961 → 1073
    Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
    cd00200
    Location:3 → 324
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:14 → 51
    7WD40; WD40 repeat [structural motif]
    cl02556
    Location:1142 → 1223
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
Nucleotide Protein
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