U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ryr2 ryanodine receptor 2 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100774683, updated on 8-Mar-2024

Summary

Gene symbol
Ryr2
Gene description
ryanodine receptor 2
Locus tag
I79_012424
See related
Ensembl:ENSCGRG00015013449
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 3
Exon count:
105
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614131.1 (716462..1118981, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 3 NC_048596.1 (235528307..235929563, complement)

NW_003614131.1Genomic Context describing neighboring genes Neighboring gene long-chain-fatty-acid--CoA ligase 5-like Neighboring gene zona pellucida glycoprotein 4

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ryanodine-sensitive calcium-release channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of calcium channel complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in sarcoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in smooth endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ryanodine receptor 2
Names
ryanodine receptor 2 (cardiac)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614131.1 Reference CriGri_1.0 Primary Assembly

    Range
    716462..1118981 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035457661.1XP_035313552.1  ryanodine receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2LGP5
    Conserved Domains (11) summary
    cd12877
    Location:666817
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10981230
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14241571
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:47374897
    Ion_trans; Ion transport protein
    pfam01365
    Location:467660
    RYDR_ITPR; RIH domain
    pfam02026
    Location:27142804
    RyR; RyR domain
    pfam02815
    Location:238418
    MIR; MIR domain
    pfam06459
    Location:43534618
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:38503967
    RIH_assoc; RyR and IP3R Homology associated
    pfam13499
    Location:40514106
    EF-hand_7; EF-hand domain pair
    cl19745
    Location:30234
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048596.1 Alternate CriGri-PICRH-1.0

    Range
    235528307..235929563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035441718.1XP_035297609.1  ryanodine receptor 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LGP5, A0A9J7GR85
    Related
    ENSCGRP00015018208.2, ENSCGRT00015022365.2
    Conserved Domains (11) summary
    cd12877
    Location:644795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:10761208
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:14021549
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:47154875
    Ion_trans; Ion transport protein
    pfam01365
    Location:445638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:26922782
    RyR; RyR domain
    pfam02815
    Location:216396
    MIR; MIR domain
    pfam06459
    Location:43314596
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:38283945
    RIH_assoc; RyR and IP3R Homology associated
    pfam13499
    Location:40294084
    EF-hand_7; EF-hand domain pair
    cl19745
    Location:8212
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor