U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rgs12 regulator of G protein signaling 12 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100765309, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Rgs12
Gene description
regulator of G protein signaling 12
Locus tag
I79_002030
See related
Ensembl:ENSCGRG00015026056
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613629.1 (227902..308183)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (103944777..104041144)

NW_003613629.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 D4-like Neighboring gene huntingtin Neighboring gene Myb/SANT DNA binding domain containing 1 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene HGF activator Neighboring gene docking protein 7

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
regulator of G-protein signaling 12
Names
regulator of G-protein signaling 12-like protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613629.1 Reference CriGri_1.0 Primary Assembly

    Range
    227902..308183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007651573.4 → XP_007649763.1  regulator of G-protein signaling 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C2LQG1
    Conserved Domains (9) summary
    smart00455
    Location:1034 → 1103
    RBD; Raf-like Ras-binding domain
    cd01817
    Location:962 → 1034
    RGS12_RBD; Ubiquitin domain of RGS12 and RGS14
    cd08742
    Location:715 → 829
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    cd00992
    Location:19 → 95
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:227 → 358
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    pfam02188
    Location:1187 → 1208
    GoLoco; GoLoco motif
    pfam16611
    Location:1105 → 1175
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:1250 → 1383
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:835 → 932
    RGS12_us1; Unstructured region of RGS12

  2. XM_035461954.1 → XP_035317845.1  regulator of G-protein signaling 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LQG1
    Conserved Domains (9) summary
    cd08742
    Location:715 → 829
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    smart00390
    Location:1179 → 1199
    GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
    cd00992
    Location:19 → 95
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:227 → 358
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    cd17136
    Location:961 → 1030
    RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
    pfam16611
    Location:1105 → 1136
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:1228 → 1377
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:835 → 948
    RGS12_us1; Unstructured region of RGS12
    cl28922
    Location:1031 → 1103
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  3. XM_027384005.2 → XP_027239806.1  regulator of G-protein signaling 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C2LV60

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276807.1 Alternate CriGri-PICRH-1.0

    Range
    103944777..104041144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027387131.2 → XP_027242932.1  regulator of G-protein signaling 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C2LQG1, A0A9J7HAV6
    Related
    ENSCGRP00015035174.1, ENSCGRT00015042849.2
    Conserved Domains (9) summary
    cd08742
    Location:715 → 829
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    smart00390
    Location:1187 → 1208
    GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
    cd00992
    Location:19 → 95
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:227 → 358
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    cd17136
    Location:961 → 1030
    RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
    pfam16611
    Location:1105 → 1179
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:1237 → 1392
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:835 → 948
    RGS12_us1; Unstructured region of RGS12
    cl28922
    Location:1031 → 1103
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  2. XM_035452636.1 → XP_035308527.1  regulator of G-protein signaling 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LQG1, A0A9J7HAB5
    Conserved Domains (9) summary
    cd08742
    Location:715 → 829
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    smart00390
    Location:1179 → 1199
    GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
    cd00992
    Location:19 → 95
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:227 → 358
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    cd17136
    Location:961 → 1030
    RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
    pfam16611
    Location:1105 → 1136
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:1228 → 1383
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:835 → 948
    RGS12_us1; Unstructured region of RGS12
    cl28922
    Location:1031 → 1103
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  3. XM_035452637.1 → XP_035308528.1  regulator of G-protein signaling 12 isoform X4

    UniProtKB/TrEMBL
    A0A9J7HDV4
    Related
    ENSCGRP00015035186.2, ENSCGRT00015042861.2
    Conserved Domains (7) summary
    cd08742
    Location:715 → 829
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    cd00992
    Location:19 → 95
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:227 → 358
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    cd17136
    Location:961 → 1030
    RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
    pfam16611
    Location:1105 → 1136
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16613
    Location:835 → 948
    RGS12_us1; Unstructured region of RGS12
    cl28922
    Location:1031 → 1103
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  4. XM_035452635.1 → XP_035308526.1  regulator of G-protein signaling 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C2LQG1, A0A9J7HAV6
    Conserved Domains (9) summary
    cd08742
    Location:715 → 829
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    smart00390
    Location:1187 → 1208
    GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
    cd00992
    Location:19 → 95
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:227 → 358
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    cd17136
    Location:961 → 1030
    RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
    pfam16611
    Location:1105 → 1179
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:1237 → 1392
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:835 → 948
    RGS12_us1; Unstructured region of RGS12
    cl28922
    Location:1031 → 1103
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  5. XM_035452638.1 → XP_035308529.1  regulator of G-protein signaling 12 isoform X3

    UniProtKB/TrEMBL
    A0A8C2LV60, A0A9J7KF73
    Related
    ENSCGRP00015035240.2, ENSCGRT00015042917.2
    Conserved Domains (7) summary
    cd08742
    Location:68 → 182
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    smart00390
    Location:540 → 561
    GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
    cd17136
    Location:314 → 383
    RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
    pfam16611
    Location:458 → 532
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:590 → 745
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:188 → 301
    RGS12_us1; Unstructured region of RGS12
    cl28922
    Location:384 → 456
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.