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Fn1 fibronectin 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100732865, updated on 8-Mar-2024

Summary

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Gene symbol
Fn1
Gene description
fibronectin 1
See related
Ensembl:ENSCPOG00000012808
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Fn1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
46
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947509.1 (52347322..52408839, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176406.1 (47625076..47686618, complement)

NW_026947509.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 12 Neighboring gene 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Neighboring gene uncharacterized LOC106028596 Neighboring gene importin subunit alpha-1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables proteoglycan binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-substrate junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibronectin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947509.1 Reference mCavPor4.1

    Range
    52347322..52408839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063237461.1 → XP_063093531.1  fibronectin isoform X8

  2. XM_003474207.5 → XP_003474255.1  fibronectin isoform X5

    UniProtKB/TrEMBL
    A0A286XB48
    Related
    ENSCPOP00000022636.1
    Conserved Domains (6) summary
    smart00059
    Location:355 → 403
    FN2; Fibronectin type 2 domain
    smart00058
    Location:187 → 231
    FN1; Fibronectin type 1 domain
    cd00061
    Location:53 → 90
    FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
    cd00063
    Location:1815 → 1895
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00039
    Location:232 → 271
    fn1; Fibronectin type I domain
    pfam00041
    Location:1450 → 1531
    fn3; Fibronectin type III domain

  3. XM_063237460.1 → XP_063093530.1  fibronectin isoform X7

  4. XM_005005775.4 → XP_005005832.1  fibronectin isoform X3

    UniProtKB/TrEMBL
    A0A286XIX4
    Related
    ENSCPOP00000025271.1
    Conserved Domains (6) summary
    smart00059
    Location:355 → 403
    FN2; Fibronectin type 2 domain
    smart00058
    Location:187 → 231
    FN1; Fibronectin type 1 domain
    cd00061
    Location:53 → 90
    FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
    cd00063
    Location:1905 → 1985
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00039
    Location:232 → 271
    fn1; Fibronectin type I domain
    pfam00041
    Location:1450 → 1531
    fn3; Fibronectin type III domain

  5. XM_063237459.1 → XP_063093529.1  fibronectin isoform X6

  6. XM_013157425.3 → XP_013012879.1  fibronectin isoform X2

    Conserved Domains (6) summary
    smart00059
    Location:355 → 403
    FN2; Fibronectin type 2 domain
    smart00058
    Location:187 → 231
    FN1; Fibronectin type 1 domain
    cd00061
    Location:53 → 90
    FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
    cd00063
    Location:1906 → 1986
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00039
    Location:232 → 271
    fn1; Fibronectin type I domain
    pfam00041
    Location:1541 → 1622
    fn3; Fibronectin type III domain

  7. XM_063237458.1 → XP_063093528.1  fibronectin isoform X4

  8. XM_003474205.5 → XP_003474253.1  fibronectin isoform X1

    UniProtKB/TrEMBL
    H0VMA2
    Related
    ENSCPOP00000011528.2
    Conserved Domains (6) summary
    smart00059
    Location:355 → 403
    FN2; Fibronectin type 2 domain
    smart00058
    Location:187 → 231
    FN1; Fibronectin type 1 domain
    cd00061
    Location:53 → 90
    FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
    cd00063
    Location:1996 → 2076
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00039
    Location:232 → 271
    fn1; Fibronectin type I domain
    pfam00041
    Location:1541 → 1622
    fn3; Fibronectin type III domain
Nucleotide Protein
Heading Accession and Version

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