Uhrf2 ubiquitin like with PHD and ring finger domains 2 [Cavia porcellus (domestic guinea pig)] - Gene

Summary

Gene symbol: Uhrf2
Gene description: ubiquitin like with PHD and ring finger domains 2
See related: Ensembl:ENSCPOG00000004838
Gene type: protein coding
RefSeq status: MODEL
Organism: Cavia porcellus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Un

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	mCavPor4.1 (GCF_034190915.1)	Unplaced Scaffold	NW_026947484.1 (82111385..82188247)
103	previous assembly	Cavpor3.0 (GCF_000151735.1)	Unplaced Scaffold	NT_176398.1 (13551151..13628252, complement)

NW_026947484.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of gene expression via chromosomal CpG island methylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase UHRF2

Names: ubiquitin-like, containing PHD and RING finger domains 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

NW_026947484.1 Reference mCavPor4.1

Range

82111385..82188247

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063250947.1 → XP_063107017.1 E3 ubiquitin-protein ligase UHRF2 isoform X2
XM_005004713.4 → XP_005004770.1 E3 ubiquitin-protein ligase UHRF2 isoform X3

Conserved Domains (6) summary

cd01797
Location:1 → 78

NIRF_N; amino-terminal ubiquitin-like domain of Np95 and NIRF

smart00213
Location:3 → 74

UBQ; Ubiquitin homologues

cd00162
Location:648 → 691

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd15617
Location:347 → 393

PHD_UHRF2; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 2 (UHRF2)

pfam02182
Location:447 → 615

SAD_SRA; SAD/SRA domain

pfam12148
Location:126 → 313

TTD; Tandem tudor domain within UHRF1
XM_003472174.5 → XP_003472222.1 E3 ubiquitin-protein ligase UHRF2 isoform X1

UniProtKB/TrEMBL

H0V426

Related

ENSCPOP00000004353.2

Conserved Domains (6) summary

cd01797
Location:1 → 78

NIRF_N; amino-terminal ubiquitin-like domain of Np95 and NIRF

smart00213
Location:3 → 74

UBQ; Ubiquitin homologues

cd00162
Location:733 → 776

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

cd15617
Location:347 → 393

PHD_UHRF2; PHD finger found in ubiquitin-like PHD and RING finger domain-containing protein 2 (UHRF2)

pfam02182
Location:447 → 615

SAD_SRA; SAD/SRA domain

pfam12148
Location:126 → 313

TTD; Tandem tudor domain within UHRF1
XM_063250954.1 → XP_063107024.1 E3 ubiquitin-protein ligase UHRF2 isoform X4