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isl2a ISL LIM homeobox 2a [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100710471, updated on 8-Mar-2024

Summary

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Gene symbol
isl2a
Gene description
ISL LIM homeobox 2a
See related
Ensembl:ENSONIG00000015258
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Also known as
isl2
Expression
Biased expression in whole embryo (RPKM 3.0) and testis (RPKM 0.2) See more
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG7
Exon count:
6
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG7 NC_031972.2 (52805938..52810496)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG7 NC_031972.1 (44353930..44358380, complement)

Linkage Group LG7 - NC_031972.2Genomic Context describing neighboring genes Neighboring gene transmembrane protein 266 Neighboring gene neuregulin 4 Neighboring gene electron transfer flavoprotein subunit alpha Neighboring gene S-phase cyclin A-associated protein in the ER Neighboring gene reticulocalbin 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Oreochromis niloticus Transcriptome or Gene expression Oreochromis niloticus Transcriptome or Gene expression
  • Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
  • BioProject: PRJNA78915
  • Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin gene enhancer protein ISL-2
Names
ISL LIM homeobox 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031972.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    52805938..52810496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003440420.5 → XP_003440468.1  insulin gene enhancer protein ISL-2

    UniProtKB/TrEMBL
    I3KDK4
    Related
    ENSONIP00000019199.2, ENSONIT00000019216.2
    Conserved Domains (4) summary
    cd09366
    Location:27 → 81
    LIM1_Isl; The first LIM domain of Isl, a member of LHX protein family
    cd09374
    Location:89 → 143
    LIM2_Isl; The second LIM domain of Isl, a member of LHX protein family
    smart00389
    Location:191 → 247
    HOX; Homeodomain
    COG5576
    Location:187 → 301
    COG5576; Homeodomain-containing transcription factor [Transcription]
Nucleotide Protein
Heading Accession and Version

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