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TXNRD3 thioredoxin reductase 3 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100670423, updated on 11-Apr-2024

Summary

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Gene symbol
TXNRD3
Gene description
thioredoxin reductase 3
See related
EnsemblRapid:ENSLAFG00000013303
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 22 NC_087363.1 (32988825..33076560, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573432.1 (27636368..27721632, complement)

Chromosome 22 - NC_087363.1Genomic Context describing neighboring genes Neighboring gene chromosome 22 C3orf22 homolog Neighboring gene carbohydrate sulfotransferase 13 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 6 Neighboring gene plexin A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glutathione-disulfide reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thioredoxin-disulfide reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thioredoxin reductase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087363.1 Reference mLoxAfr1.hap2

    Range
    32988825..33076560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023547847.2 → XP_023403615.1  thioredoxin reductase 3

    UniProtKB/TrEMBL
    G3TB25
    Related
    ENSLAFP00000038724.1, ENSLAFT00000045461.1
    Conserved Domains (2) summary
    cd03419
    Location:1 → 80
    GRX_GRXh_1_2_like; Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, ...
    cl27343
    Location:95 → 581
    Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
Nucleotide Protein
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