U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SLIT2 slit guidance ligand 2 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100663413, updated on 6-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
SLIT2
Gene description
slit guidance ligand 2
See related
EnsemblRapid:ENSLAFG00000017738
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 5 NC_087346.1 (140695721..141113941, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573438.1 (19787538..20206677)

Chromosome 5 - NC_087346.1Genomic Context describing neighboring genes Neighboring gene dnaJ homolog subfamily B member 6-like Neighboring gene parkin coregulated like Neighboring gene NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial-like Neighboring gene ligand dependent nuclear receptor corepressor like Neighboring gene non-SMC condensin I complex subunit G

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Roundabout binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell growth IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinal ganglion cell axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
slit homolog 2 protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087346.1 Reference mLoxAfr1.hap2

    Range
    140695721..141113941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003411373.4 → XP_003411421.1  slit homolog 2 protein isoform X2

    UniProtKB/TrEMBL
    G3TJH2
    Related
    ENSLAFP00000037708.1, ENSLAFT00000058831.1
    Conserved Domains (10) summary
    smart00013
    Location:727 → 758
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:859 → 908
    LRRCT; Leucine rich repeat C-terminal domain
    smart00282
    Location:1183 → 1317
    LamG; Laminin G domain
    cd00054
    Location:1076 → 1112
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00116
    Location:43 → 214
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:38 → 56
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00008
    Location:961 → 994
    EGF; EGF-like domain
    pfam12799
    Location:324 → 364
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:777 → 837
    LRR_8; Leucine rich repeat
    cl15307
    Location:664 → 713
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  2. XM_064286010.1 → XP_064142080.1  slit homolog 2 protein isoform X1

    UniProtKB/TrEMBL
    G3TJH2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.