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TRAF4 TNF receptor associated factor 4 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100660891, updated on 11-Apr-2024

Summary

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Gene symbol
TRAF4
Gene description
TNF receptor associated factor 4
See related
EnsemblRapid:ENSLAFG00000013400
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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See TRAF4 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 18 NC_087359.1 (60029977..60035972)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573467.1 (1740267..1746330)

Chromosome 18 - NC_087359.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA Z17 Neighboring gene protein FAM222B Neighboring gene ribosomal protein L23a Neighboring gene NIMA related kinase 8 Neighboring gene large ribosomal subunit protein eL19-like Neighboring gene Era like 12S mitochondrial rRNA chaperone 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of NF-kappaB-inducing kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087359.1 Reference mLoxAfr1.hap2

    Range
    60029977..60035972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003416966.3 → XP_003417014.1  TNF receptor-associated factor 4

    UniProtKB/TrEMBL
    G3TB84
    Related
    ENSLAFP00000047414.1, ENSLAFT00000049497.1
    Conserved Domains (3) summary
    cd00162
    Location:18 → 55
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    cd03781
    Location:308 → 463
    MATH_TRAF4; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF4 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF4, including the Drosophila protein DTRAF1. TRAF molecules serve as adapter ...
    pfam02176
    Location:210 → 269
    zf-TRAF; TRAF-type zinc finger
Nucleotide Protein
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