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TGFBR2 transforming growth factor beta receptor 2 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100606849, updated on 8-Mar-2024

Summary

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Gene symbol
TGFBR2
Gene description
transforming growth factor beta receptor 2
See related
EnsemblRapid:ENSNLEG00000004162
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 4 NC_044384.1 (120728763..120816072, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 4 NC_019819.1 (121912795..122004390, complement)

Chromosome 4 - NC_044384.1Genomic Context describing neighboring genes Neighboring gene calponin-2 pseudogene Neighboring gene glutamate decarboxylase like 1 Neighboring gene uncharacterized LOC115834721 Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor activity, type II IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type I transforming growth factor beta receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TGF-beta receptor type-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044384.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    120728763..120816072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003256801.4 → XP_003256849.1  TGF-beta receptor type-2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3H3F9
    Related
    ENSNLEP00000046750.2, ENSNLET00000040386.2
    Conserved Domains (2) summary
    cd14055
    Location:248 → 542
    STKc_TGFbR2_like; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Type II Receptor
    pfam08917
    Location:49 → 159
    ecTbetaR2; Transforming growth factor beta receptor 2 ectodomain

  2. XM_003256802.4 → XP_003256850.1  TGF-beta receptor type-2 isoform X1

    UniProtKB/TrEMBL
    G1QVR5
    Related
    ENSNLEP00000005036.1, ENSNLET00000005296.3
    Conserved Domains (2) summary
    cd14055
    Location:273 → 567
    STKc_TGFbR2_like; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Type II Receptor
    pfam08917
    Location:74 → 184
    ecTbetaR2; Transforming growth factor beta receptor 2 ectodomain
Nucleotide Protein
Heading Accession and Version

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