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SF1 splicing factor 1 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100604364, updated on 8-Mar-2024

Summary

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Gene symbol
SF1
Gene description
splicing factor 1
See related
EnsemblRapid:ENSNLEG00000005236
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 4 NC_044384.1 (84374630..84389885, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 4 NC_019819.1 (85205997..85220387, complement)

Chromosome 4 - NC_044384.1Genomic Context describing neighboring genes Neighboring gene RAS guanyl releasing protein 2 Neighboring gene glycogen phosphorylase, muscle associated Neighboring gene mitogen-activated protein kinase kinase kinase kinase 2 Neighboring gene menin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
splicing factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044384.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    84374630..84389885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012497824.2 → XP_012353278.2  splicing factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A2I3GTB5
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  2. XM_004087834.3 → XP_004087882.2  splicing factor 1 isoform X9

    UniProtKB/TrEMBL
    A0A2I3HLQ1
    Related
    ENSNLEP00000006411.3, ENSNLET00000006737.4
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  3. XM_012497831.1 → XP_012353285.1  splicing factor 1 isoform X11

    UniProtKB/TrEMBL
    A0A2I3HLQ1
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  4. XM_030811120.1 → XP_030666980.1  splicing factor 1 isoform X14

    Conserved Domains (2) summary
    smart00343
    Location:163 → 178
    ZnF_C2HC; zinc finger
    cd02395
    Location:22 → 140
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...

  5. XM_030811114.1 → XP_030666974.1  splicing factor 1 isoform X4

    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  6. XM_030811112.1 → XP_030666972.1  splicing factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3HLQ1
    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  7. XM_030811111.1 → XP_030666971.1  splicing factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3GTB5
    Related
    ENSNLEP00000034492.2, ENSNLET00000057092.2
    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  8. XM_030811116.1 → XP_030666976.1  splicing factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A2I3HLQ1
    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  9. XM_030811115.1 → XP_030666975.1  splicing factor 1 isoform X5

    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  10. XM_030811113.1 → XP_030666973.1  splicing factor 1 isoform X3

    Conserved Domains (2) summary
    smart00343
    Location:252 → 267
    ZnF_C2HC; zinc finger
    COG5176
    Location:10 → 231
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  11. XM_030811122.1 → XP_030666982.1  splicing factor 1 isoform X15

    Conserved Domains (2) summary
    smart00343
    Location:163 → 178
    ZnF_C2HC; zinc finger
    cd22382
    Location:20 → 112
    KH-I_SF1; type I K homology (KH) RNA-binding domain found in splicing factor 1 (SF1) and similar proteins

  12. XM_003274165.4 → XP_003274213.1  splicing factor 1 isoform X6

    Conserved Domains (2) summary
    smart00343
    Location:405 → 420
    ZnF_C2HC; zinc finger
    COG5176
    Location:144 → 384
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  13. XM_004087835.3 → XP_004087883.1  splicing factor 1 isoform X13

    See identical proteins and their annotated locations for XP_004087883.1

    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  14. XM_030811117.1 → XP_030666977.1  splicing factor 1 isoform X10

    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  15. XM_030811118.1 → XP_030666978.1  splicing factor 1 isoform X12

    UniProtKB/TrEMBL
    A0A2I3HLQ1
    Conserved Domains (2) summary
    smart00343
    Location:278 → 293
    ZnF_C2HC; zinc finger
    COG5176
    Location:17 → 257
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  16. XM_030811121.1 → XP_030666981.1  splicing factor 1 isoform X15

    Conserved Domains (2) summary
    smart00343
    Location:163 → 178
    ZnF_C2HC; zinc finger
    cd22382
    Location:20 → 112
    KH-I_SF1; type I K homology (KH) RNA-binding domain found in splicing factor 1 (SF1) and similar proteins
Nucleotide Protein
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