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EGF epidermal growth factor [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100588963, updated on 8-Mar-2024

Summary

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Gene symbol
EGF
Gene description
epidermal growth factor
See related
EnsemblRapid:ENSNLEG00000016536
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See EGF in Genome Data Viewer
Location:
chromosome: 18
Exon count:
24
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 18 NC_044398.1 (58854589..58957279)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 18 NC_019833.1 (60040959..60142121)

Chromosome 18 - NC_044398.1Genomic Context describing neighboring genes Neighboring gene keratin, type I cytoskeletal 19 pseudogene Neighboring gene leucine rich repeat, Ig-like and transmembrane domains 3 Neighboring gene U6 spliceosomal RNA Neighboring gene ELOVL fatty acid elongase 6 Neighboring gene heat shock factor-binding protein 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-epidermal growth factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044398.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    58854589..58957279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030798013.1 → XP_030653873.1  pro-epidermal growth factor isoform X4

    UniProtKB/TrEMBL
    A0A2I3HAR9
    Related
    ENSNLEP00000040734.2, ENSNLET00000054235.2
    Conserved Domains (5) summary
    PHA03099
    Location:853 → 891
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    smart00135
    Location:505 → 545
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:314 → 353
    EGF_CA; Calcium-binding EGF-like domain
    pfam07645
    Location:789 → 817
    EGF_CA; Calcium-binding EGF domain
    pfam14670
    Location:703 → 738
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_003269351.4 → XP_003269399.3  pro-epidermal growth factor isoform X1

    UniProtKB/TrEMBL
    G1S3J7
    Conserved Domains (7) summary
    PHA03099
    Location:976 → 1014
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    smart00135
    Location:547 → 587
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:870 → 910
    EGF_CA; Calcium-binding EGF-like domain
    pfam07645
    Location:912 → 940
    EGF_CA; Calcium-binding EGF domain
    pfam00008
    Location:835 → 864
    EGF; EGF-like domain
    pfam12662
    Location:336 → 359
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:745 → 780
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_003269352.4 → XP_003269400.3  pro-epidermal growth factor isoform X3

    UniProtKB/TrEMBL
    A0A2I3GH31

  4. XM_003269353.4 → XP_003269401.3  pro-epidermal growth factor isoform X2

    UniProtKB/TrEMBL
    A0A2I3HAR9
    Conserved Domains (6) summary
    PHA03099
    Location:934 → 972
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    smart00135
    Location:505 → 545
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:828 → 868
    EGF_CA; Calcium-binding EGF-like domain
    pfam07645
    Location:870 → 898
    EGF_CA; Calcium-binding EGF domain
    pfam00008
    Location:793 → 822
    EGF; EGF-like domain
    pfam14670
    Location:703 → 738
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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