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pdgfrb platelet-derived growth factor receptor, beta polypeptide [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100487523, updated on 18-Sep-2024

Summary

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Official Symbol
pdgfrbprovided by Xenbase
Official Full Name
platelet-derived growth factor receptor, beta polypeptideprovided by Xenbase
Primary source
Xenbase:XB-GENE-6096145
See related
Ensembl:ENSXETG00000031823
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
pdgfr1; pdgfr-beta
Orthologs
human mouse all
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Genomic context

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See pdgfrb in Genome Data Viewer
Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (21192172..21264186)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (7242510..7314190, complement)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 7 Neighboring gene caudal type homeobox 1 Neighboring gene colony stimulating factor 1 receptor Neighboring gene uncharacterized LOC105946788

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing. Doherty L, et al. PLoS One, 2019. PMID 31665177, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PDGFRbeta signaling through PI3K is necessary for robust periosteal activation in the earliest phases of fracture healing
    Title: A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
platelet-derived growth factor receptor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    21192172..21264186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012959674.2 → XP_012815128.1  platelet-derived growth factor receptor beta

    See identical proteins and their annotated locations for XP_012815128.1

    UniProtKB/TrEMBL
    A0A6I8SLH0
    Related
    ENSXETP00000095686.2, ENSXETT00000072802.2
    Conserved Domains (2) summary
    cl11960
    Location:298 → 399
    Ig; Immunoglobulin domain
    cl21453
    Location:549 → 946
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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