ITPR1 inositol 1,4,5-trisphosphate receptor type 1 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: ITPR1
Gene description: inositol 1,4,5-trisphosphate receptor type 1
Locus tag: CR201_G0011352
See related: Ensembl:ENSPPYG00000013697
Gene type: protein coding
RefSeq status: MODEL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 59

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	2	NC_085928.1 (73987029..74341476, complement)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	3	NC_071988.1 (61964662..62318484, complement)

Chromosome 2 - NC_085928.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-59934 (e-PCR)
- UniSTS:20993

D3S3340 (e-PCR)
- UniSTS:25345

SHGC-76664 (e-PCR)
- UniSTS:78111

ha3079 (e-PCR)
- UniSTS:515639

ITPR1 (e-PCR)
- UniSTS:479831

D3S1750E (e-PCR)
- UniSTS:473194

SHGC-147293 (e-PCR)
- UniSTS:175725

IB262 (e-PCR)
- UniSTS:61846

RH68059 (e-PCR)
- UniSTS:46758

RH104411 (e-PCR)
- UniSTS:98736

RH102411 (e-PCR)
- UniSTS:96745

G19634 (e-PCR)
- UniSTS:9965

A001T36 (e-PCR)
- UniSTS:9966

SHGC-50648 (e-PCR)
- UniSTS:13811

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables inositol 1,4,5 trisphosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables inositol 1,4,5-trisphosphate-gated calcium channel activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in calcium ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: inositol 1,4,5-trisphosphate receptor type 1

Names: inositol 1,4,5-triphosphate receptor, type 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_085928.1 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

73987029..74341476 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024244292.3 → XP_024100060.3 inositol 1,4,5-trisphosphate receptor type 1 isoform X3

UniProtKB/TrEMBL

A0A2J8WE33
XM_009238773.4 → XP_009237048.3 inositol 1,4,5-trisphosphate receptor type 1 isoform X1

UniProtKB/TrEMBL

A0A2J8WE19, H2PA73
XM_024244293.3 → XP_024100061.3 inositol 1,4,5-trisphosphate receptor type 1 isoform X4

UniProtKB/TrEMBL

A0A2J8WE33, A0A2J8WE60
XM_024244291.3 → XP_024100059.3 inositol 1,4,5-trisphosphate receptor type 1 isoform X2

UniProtKB/TrEMBL

A0A2J8WE19, A0A2J8WE37, A0A8I5UEP6, H2PA73