MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: MAP4K2
Gene description: mitogen-activated protein kinase kinase kinase kinase 2
Locus tag: CR201_G0031347
See related: Ensembl:ENSPPYG00000003096
Gene type: protein coding
RefSeq status: MODEL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	9	NC_071994.2 (9893020..9906722)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	11	NC_071996.1 (9870694..9884350)

Chromosome 9 - NC_071994.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

ECD05678 (e-PCR)
- UniSTS:286740

stSG635686 (e-PCR)
- UniSTS:460862

stSG635688 (e-PCR)
- UniSTS:460864

ECD08296 (e-PCR)
- UniSTS:289344

stSG635689 (e-PCR)
- UniSTS:460865

stSG635690 (e-PCR)
- UniSTS:460866

stSG635691 (e-PCR)
- UniSTS:460867

stSG635692 (e-PCR)
- UniSTS:460868

stSG635696 (e-PCR)
- UniSTS:460872

stSG635697 (e-PCR)
- UniSTS:460873

REN56457 (e-PCR)
- UniSTS:381257

stSG635698 (e-PCR)
- UniSTS:460874

REN56458 (e-PCR)
- UniSTS:381258

stSG635700 (e-PCR)
- UniSTS:460875

REN56459 (e-PCR)
- UniSTS:381259

RH68087 (e-PCR)
- UniSTS:17485

REN56461 (e-PCR)
- UniSTS:381261

REN56462 (e-PCR)
- UniSTS:381262

REN56463 (e-PCR)
- UniSTS:381263

REN56467 (e-PCR)
- UniSTS:381267

REN56471 (e-PCR)
- UniSTS:381271

ECD04713 (e-PCR)
- UniSTS:285784

ECD24256 (e-PCR)
- UniSTS:305240

REN56473 (e-PCR)
- UniSTS:381273

REN56474 (e-PCR)
- UniSTS:381274

REN56475 (e-PCR)
- UniSTS:381275

REN56477 (e-PCR)
- UniSTS:381277

REN56478 (e-PCR)
- UniSTS:381278

REN56479 (e-PCR)
- UniSTS:381279

REN56480 (e-PCR)
- UniSTS:381280

REN56481 (e-PCR)
- UniSTS:381281

REN56483 (e-PCR)
- UniSTS:381283

REN56484 (e-PCR)
- UniSTS:381284

REN56488 (e-PCR)
- UniSTS:381288

REN56492 (e-PCR)
- UniSTS:381292

REN56493 (e-PCR)
- UniSTS:381293

REN56494 (e-PCR)
- UniSTS:381294

REN56495 (e-PCR)
- UniSTS:381295

MARC_4707-4708:966894283:1 (e-PCR)
- UniSTS:269424

ECD10914 (e-PCR)
- UniSTS:291953

REN56497 (e-PCR)
- UniSTS:381297

REN56498 (e-PCR)
- UniSTS:381298

REN56499 (e-PCR)
- UniSTS:381299

REN56501 (e-PCR)
- UniSTS:381301

REN56504 (e-PCR)
- UniSTS:381304

REN56505 (e-PCR)
- UniSTS:381305

REN56506 (e-PCR)
- UniSTS:381306

REN56507 (e-PCR)
- UniSTS:381307

REN56508 (e-PCR)
- UniSTS:381308

REN56509 (e-PCR)
- UniSTS:381309

REN56510 (e-PCR)
- UniSTS:381310

REN56511 (e-PCR)
- UniSTS:381311

REN56512 (e-PCR)
- UniSTS:381312

REN56513 (e-PCR)
- UniSTS:381313

REN56514 (e-PCR)
- UniSTS:381314

REN56515 (e-PCR)
- UniSTS:381315

REN56516 (e-PCR)
- UniSTS:381316

STS-U07349 (e-PCR)
- UniSTS:49029

REN56517 (e-PCR)
- UniSTS:381317

REN56518 (e-PCR)
- UniSTS:381318

REN56519 (e-PCR)
- UniSTS:381319

REN56520 (e-PCR)
- UniSTS:381320

REN56521 (e-PCR)
- UniSTS:381321

REN56522 (e-PCR)
- UniSTS:381322

REN56523 (e-PCR)
- UniSTS:381323

REN56524 (e-PCR)
- UniSTS:381324

ECD20969 (e-PCR)
- UniSTS:301966

ECD10954 (e-PCR)
- UniSTS:291991

ECD08405 (e-PCR)
- UniSTS:289453

WI-18813 (e-PCR)
- UniSTS:18617

MAP4K2_2786 (e-PCR)
- UniSTS:471491

ECD06366 (e-PCR)
- UniSTS:287428

ECD00438 (e-PCR)
- UniSTS:281549

ECD05867 (e-PCR)
- UniSTS:286929

ECD08965 (e-PCR)
- UniSTS:290011

ECD00208 (e-PCR)
- UniSTS:281322

D20S991 (e-PCR)
- UniSTS:154606

ECD11303 (e-PCR)
- UniSTS:292339

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables MAP kinase kinase kinase kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: mitogen-activated protein kinase kinase kinase kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_071994.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

9893020..9906722

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024255929.3 → XP_024111697.1 mitogen-activated protein kinase kinase kinase kinase 2 isoform X3

UniProtKB/TrEMBL

A0A2J8TYU0, A0A2J8TYU1, H2NCY9

Related

ENSPPYP00000003581.3

Conserved Domains (2) summary

smart00036
Location:488 → 800

CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2

cd06613
Location:16 → 272

STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
XM_054525669.2 → XP_054381644.1 mitogen-activated protein kinase kinase kinase kinase 2 isoform X1
XM_063728380.1 → XP_063584450.1 mitogen-activated protein kinase kinase kinase kinase 2 isoform X2
XM_063728381.1 → XP_063584451.1 mitogen-activated protein kinase kinase kinase kinase 2 isoform X4

UniProtKB/TrEMBL

A0A2J8TYT3, A0A2J8TYU0